Hosted by the Circuit Neuroscience research group (CNS)
The dorsal striatum receives a major and topographic input from the cortex, and the cortex and striatum are thought to work together to carry out a diverse set of functions. It is unclear how the cortex and striatum influence each other however, and it has been suggested that each carries distinct sensorimotor correlates to serve complementary roles. We sought to record from connected regions of the cortex and striatum in mice during sensory guided behavior to determine the relationship of activity across structures. We found precise spatial correlations in activity following anatomical projections from the cortex to the striatum, and activity in the striatum reflected that in associated cortical regions consistently across behavioral contexts. This match in activity was scaled by learning, as untrained mice exhibited smaller sensory responses selectively in the striatum. These results suggest a simple and scalable mapping of activity between the cortex and striatum.
For those wishing to take part online:
- Join Zoom Meeting: https://bristol-ac-uk.zoom.us/j/93448809055?pwd=dlh1Y1dTMkRIL3B2bWphOEhZQlhLQT09
- Meeting ID: 934 4880 9055
- Passcode: 912378
The CNS group will be hosting a social in the space next to The Source between 17.00-18.30. Food and drinks will be provided and this is generously supported by the BNA.
If you would like to meet with Andy on the day contact Paul Anastasiades.