Micro Electron Diffraction in a Cryo Electron Microscope : A powerful Tool for small molecule structural determination

23 January 2019, 1.00 PM - 23 January 2019, 2.00 PM

Abhay Kotecha (Thermo Scientific)

G13/14, Life Sciences Building

Hosted by the Bristol Biodesign Institute.

In the last year or so, chemists and crystallographers have realised the potential of the new breed of cryo Electron Microscopes with ultra sensitive detector systems for performing electron diffraction on powder samples. Structures can be determined at a resolution under 1 A from simple powders purely ground down to produce tiny nano crystals. The whole process can be completed in just a few hours.

This talk will describe the technique and explore how far we can go with our very own GW4 CryoTEM Talos microscope housed in the LSB and should be of great interest to chemists, crystallographers and all microscopists.

https://chemrxiv.org/articles/The_CryoEM_Method_MicroED_as_a_Powerful_Tool_for_Small_Molecule_Structure_Determination/7215332

Contact information

For further information contact j.mantell@bristol.ac.uk

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