Taming the maternal genomes
Mary Herbert (University of Newcastle)
Chemistry Lecture Theatre 3
A School of Biochemistry colloquium, hosted by Binyam Mogessie
Mary is a Professor of Reproductive Biology at Newcastle with an Honorary Consultant Clinical Scientist post with Newcastle upon Tyne Hospitals NHS Foundation Trust. She leads a team of clinical and research scientists working side by side in a programme of basic, translational and clinical science. The close integration of clinical and research scientists is a cornerstone of the research programme in her lab, with the aim to advance knowledge in the biology of germ cells and early embryos with a view to (i) improving the treatment and understanding of infertility (ii) extending the scope of reproductive technologies to prevent transmission of disease. Research interests include understanding how the zygote inherits its nuclear DNA from the male and female gametes – the oocyte and the sperm, which become haploid during a specialised form of cell division known as meiosis. By contrast, mitochondrial DNA is inherited only from the oocyte, which contains some hundreds of thousands of copies. Mary’s research has innovated pronuclear transplantation methods that can be used for the treatment of debilitating diseases brought on by mitochondrial DNA mutations.
To find out more about Mary and her work, please view this TEDMED presentation on approaches to treat mitochondrial disease.
For publications, https://www.ncl.ac.uk/igm/staff/profile/maryherbert.html#publications
If you would like to meet Mary during her visit, please contact Binyam (email@example.com)
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