Hosted by Cardiff University's School of Medicine
Abstract: The talk will describe novel single cell and spatial genomic technologies and computational workflows to dissect mechanisms of fibrosis in the kidney and the heart including cell differentiation trajectories and cellular crosstalk of key mesenchymal cells and immune cells.
Bio: Rafael Kramann is Professor of Medicine, Director of the Institute of Experimental Medicine and Systems Biology and Associate Senior Attending Renal Physician at the Department of Nephrology and Clinical Immunology at RWTH Aachen, Germany. He further directs the Laboratory of Translational Kidney and Cardiovascular Research at the Erasmus Medical Center Rotterdam, NL.
His basic and translational research focuses on understanding chronic kidney disease, cardiovascular diseases and organ fibrosis. He integrates state of the art genetic fate tracing, gene editing, single cell, multi-omics and systems biology technologies together with clinical datasets to unravel mechanisms, identify novel therapeutic targets and develop targeted therapeutics for patients with chronic kidney disease, heart failure and organ fibrosis. He is recipient of various prestigious awards, such as the Grand Prize in the Harvard Innovation Lab Dean´s Health and Lifescience Challenge 2013, the Stanley Shaldon Award of the European Renal Association (ERA-EDTA) 2014, the Nils Alwall, Carl Ludwig and Franz Volhard Awards 2014, 2015 and 2019 of the German Society of Nephrology, the Bernd Tersteegen Award 2015 of the German Dialysis Association, the Desiderius Award of the Erasmus University in 2018, the Theodor Frerichs Award of the German Society of Internal Medicine (DGIM) and the Wilhelm Vaillant Award in 2021. He is further NWO-VIDI Laureate 2021 and ERC Consolidator Grant Recipient 2022. He is coordinator of the ERA-CVD NET MEND-AGE and the BMBF CureFib consortia and PI at the British Heart Foundation Center of Excellence at the University of Edinburgh.
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Join via Zoom: https://cardiff.zoom.us/j/88372735419?pwd=djRDSmFrQkZnWFdlN2ZGdHh5WWw3UT09, Meeting ID: 883 7273 5419, Password: 909926