Unravelling the adaptive immune response in pigs

Hosted by Bristol Veterinary School

There was substantial methodological progress to dissect immune responses of livestock species in recent years. In this talk I will provide an overview of tools available to dissect T and B cells analyses in pigs. Furthermore, I will share findings how a combination of scRNA-seq and multi-dimensional flow cytometry can be used for detailed insights into local effector and regulatory phenotypes of T cells in pigs and their association with B cell and antibody responses in the context of immunisation and infection. These findings will be placed into a simple inflammation/ immunoregulation model that may help us to identify phenotypic and functional signatures associated with protective immunity.

If you would like to meet with Dr Gerner after his talk, contact Jamie Mann