Intracellular bacteria as a tool for discovery

Hosted by Bristol Veterinary School

Abstract: Bacteria have evolved to colonise almost every imaginable environment including the cells of higher organisms - a niche that presents unique challenges since these hosts have evolved potent defence mechanisms to kill invaders. Some microbes such as Anaplasma, a tick-borne pathogen which causes disease in a wide range of livestock and humans, are so well adapted to life inside other organisms that they can make a home inside immune cells, effectively disabling host defence mechanisms. In this presentation I’ll discuss my current research, which aims to define how Anaplasma and similar microbes manipulate hosts for their survival, and how this will serve as a platform for novel interventions against disease and for discoveries in fundamental biology.

If joining online: https://bristol-ac-uk.zoom.us/j/92656253459?pwd=Zk1PUUFzVVJXQzVuMkJPS2NPTGxIdz09Passcode: 186263