Using fluorescence time-lapse microscopy to visualize bacterial nanomachine behavior in microbial communities

Hosted by the School of Biochemistry

Microbial communities play a critical role in the wellbeing of the organisms that host them. However, there still remains much to learn about the intercellular interactions that shape their development. In particular, my research revolves around two short-range cell-cell interaction mechanisms, the type IV secretion system and the type VI secretion system, which facilitate horizontal spread of genetic material and mediate antibacterial antagonism, respectively. Using techniques to visualize and track the activity of these systems, we are able to uncover dynamic cellular behaviors of bacterial populations, and can begin to engineer tools that will hopefully enable us to modulate these communities.

Brian Ho's lab uses live cell imaging and biochemistry, and his talk will be focused on microbial competition. 

The talk will be followed by refreshments in the Biochemistry coffee room. If you would like to meet with Brian contact alan.cheung@bristol.ac.uk

Contact information

Enquires to alan.cheung@bristol.ac.uk