Synthesis and Catalysis Research Theme Seminar
Guest Speaker: Professor Tatiana Besset, COBRA Labs, France
Title: Modern Synthetic Solutions Towards Fluorinated Scaffolds
Abstract: Over the last years, the organofluorine research field has known a fast expansion, as shown by the plethora of pharmaceuticals and agrochemicals containing at least one fluorine atom. Consequently, a special attention was paid to the development of modern strategies in organofluorine chemistry. Besides, transition metal catalyzed direct C-H bond functionalization has known tremendous progress over the last decade allowing new retrosynthetic disconnections and innovative approaches. In that context, we focused on the development of new methodologies to introduce fluorinated groups onto molecules based on the combination of organofluorine chemistry and transition metal catalyzed C-H bond functionalization. Besides, a special attention was paid to the design of original electrophilic reagents and the synthesis of scaffolds of interest.
Academic Host: Dr Alastair Lennox