Chemical and Synthetic Biology Research Theme Seminar
Speaker: Professor Tom Muir, Princeton University
Title: Chemical Approaches to Studying Chromatin
Abstract: We are interested in studying protein function by integrating the tools of synthetic organic and physical chemistry with those of molecular genetics. Driven by a series of biological questions, we have developed general chemical biology approaches that allow the covalent structure of proteins to be manipulated with a similar level of control to that possible with smaller organic molecules. These technologies, which can be applied both in vitro and in vivo, allow the insertion of unnatural amino acids, post-translational modifications, and isotopic probes site-specifically anywhere into proteins. Our methods are now used by numerous laboratories worldwide, and have allowed a large number of biomedical questions to be addressed.
Academic Host: Dr Will Dawson
This seminar will be held online