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Douglas Lowy is the Principal Deputy Director of the National Cancer Institute (NCI), National Institutes of Health (NIH). He is also Chief of the Laboratory of Cellular Oncology in the Center for Cancer Research at NCI. He has been the NCI Principal Deputy Director since 2010, and was the Acting NCI Director three times: 2015-2017, 2019, and 2022. Prof. Lowy’s research includes the biology of papillomaviruses and the regulation of normal and neoplastic growth. The papillomavirus research is carried out in close collaboration with Dr. John Schiller, with whom he has co-authored more than 200 papers. Their laboratory was involved in the initial development, characterization, and clinical testing of the preventive virus-like particle-based HPV vaccines that are now used in the three FDA-approved HPV vaccines. His growth regulation research is now focused primarily on the DLC family of tumor suppressor genes, their mechanisms of regulation, and the potential of targeting their reactivation for the treatment of lung cancer and other malignant tumors. Prof. Lowy is a member of the National Academy of Sciences (NAS) and of the Institute of Medicine of the NAS. For their HPV vaccine research, he and Dr. Schiller have received numerous honors, including the 2007 Federal Employee of the year Service to America Medal from the Partnership for Public Service, the 2011 Gold Medal award from the Sabin Vaccine Institute, the 2012 National Medal of Technology & Innovation (awarded by President Obama in 2014), and the 2017 Lasker-DeBakey Clinical Medical Research Award.