Michael Jewett, Northwestern University

14 April 2021, 1.00 PM - 14 April 2021, 2.00 PM

Zoom webinar link: https://bristol-ac-uk.zoom.us/j/94778122664 Slido meeting number: #49281

Bioengineering beyond cells to enable a fair and sustainable 21st bio-century  

Prof. Michael Jewett
Northwestern University
Slido meeting number: #49281
Academic hosts: Thomas Gorochowski and Paul Race
 
Synthetic Biology (SB) is one of the most promising fields of research for the 21st century. SB offers powerful new ways to improve human health, build the global economy, manufacture sustainable materials, and address climate change. However, current access to SB-enabled breakthroughs is unequal, largely due to bottlenecks in infrastructure and education. Here, I describe our efforts to re-think the way we engineer biology using cell-free systems to address these bottlenecks. We show how the ability to readily store, distribute, and activate low-cost, freeze-dried cell-free systems by simply adding water has opened new opportunities for on-demand biomanufacturing of vaccines for global health, point-of-care diagnostics for environmental safety, and education for SB literacy and citizenship. By integrating cell-free systems with artificial intelligence (AI), we also show the ability to accelerate the production of carbon-negative platform chemicals. Looking forward, advances in engineering tools and new knowledge underpinning the fundamental science of living matter will ensure that SB helps solve humanity’s most pressing challenges.  

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