Current grants

May

Above & Beyond, National Child Death Registry Pilot Work. £49,769.00. April 2019 to October 2020. Peter Fleming & Peter Blair.

NIHR RfPB. Feasibility study for a randomized controlled trial comparing early prescription of near vision glasses against current standard of care for infants with perinatal brain injury. £249,905 Start 1/7/2019 for 24 months. PI Richard Bowman, Co-app Cathy Williams

National Eye Research Centre (NERC). Can handheld optical coherence tomography improve risk prediction for ROP? £69,748.46. Start 1/8/19 for 3 years. PI Prof I Gottlob (Univ of Leicester), co-app Cathy Williams
 
National Eye Research Centre (NERC). Is there a causal association between insulin signalling and myopia pathogenesis? £69,039. Start 1/10/19 for 3 years. PI Ms Denize Atan, co-apps Cathy Williams

February

British Heart Foundation Career Re-Entry Research Fellowship, Childhood diet qualirt and cardiometabolic outcomes in ALSPAC. £172,563 G Buckland


January

UoB Brigstow Institute for Refugee resilience narrative - feasibility work with Bristol Somali Community. Allport T, £6380

Ensuring financial assurance for the Nepal Injurt Research Centre programme. National Institute for Health Research. £6970, Mytton J 2019-2020

December

Nestle Nutrition. Is dietary fat intake in infancy and early childhood associated with serum leptin concentrations and body fat in later life? C Taylor (PI) and P Emmett £175,000

VTCT Foundation. Safe-Tea campaign and evaluation. A Emond (PI), A Kemp and J Mytton (co-apps). £24,750. 1st Dec 2018 for 18m
 
MRC (Confidence in Concept). Evaluating the usability, acceptability and potential effectiveness of a smartphone app to support the management of urinary incontinence and urgency in young people. Joinson C, Whale K, Yardley L, Ingram J. £76,862
 
Brigstow Institute. Support a photoexhibition launch and discussion of findings from a 'Walkabout' with Somali people in Barton Hill as an innovative methodology to critique the urban built environment in relation to opportunities for play and social interaction for preschool children from a refugee and forced migrant background. Allport T, £1000

October

Medical Research Council, Lung function trajectories from birth to school age in African children, and their early life determinants. Custovic A, Zar H, Bush A, Henderson AJ, Holloway J, Stein D, Nicol M, Gray DM. 2018-2020, £910,567

John Templeton Foundation, Transgenerational non-genetic pathways to human development. Golding J, Pembrey M, Northstone K, Williams C, Henderson J. 2018-2020, £995,500


Ongoing grants

2017 - 2018

A phase 2b Randomised, Double-blind, Placebo-controlled Study to evaluate the Safety and Efficacy of MED18897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Preterm Infants. MedImmune. Approx. £12,686 A Finn (2017 – 2018)

A Phase 3, Randomized, Observer-blind, Placebo-controlled Study to Determine the Immunogenicity and Safety of a Respiratory Synctial Virus (RSV)F Nanoparticle Vaccine With Aluminum in Healthy Third-trimester Pregnant Women; and Safety and Efficacy of Maternally Transferred Antibodies in Preventing RSV Disease in their Infants. Novavax. Up to £224,241 A Finn (2017 – 2019)

Bill and Melinda Gates Foundation. Evaluation of the relationship between pneumococcal colonisation density in 2 year old children and rates of transmission to family contacts using live attenuated intranasal influenza vaccine as a probe. A randomised prospective step-wedge multicentre study. $549,972. & Pfizer £1,766,869.12 A Finn [JO1] (Sep 2017 – Aug 2020)

BNSSG Research & Capability Fund, Injury Prevention Photosphere – further development 2018. T Deave, A Emond (UoB), B Hicks (UoB). £3000.

Economic and Social Research Council (ESRC) Impact Acceleration Account. Increasing understanding of the needs of young people with continence problems at secondary school. Carol Joinson £19,860. 1st Jan–31st Aug 2017.

Elizabeth Blackwell Institute Translational Acceleration Knowledge Transfer award, Injury Prevention Photosphere, 2017-2018. A Emond (PI, UoB), T Deave, B Hicks (UoB). £14,353.

GCRF Building Knowledge Partnerships: Bristol-Rajarata Child Injury Prevention Partnership £2,675

Global Challenges Research Fund QR Award. Culturally competent approaches to injury prevention and first response. Mytton J. £107,000. August 2018-July 2021

Global Challenges Research Fund QR Award. Interdisciplinary education for road danger reduction in Nepal. Mytton J, £90,000. August 2018-July 2021

Health Protection Research Unit - grant £22,000, Marlow R. April 2018

Linbury Trust charity. Exploring the mechanisms of action of LP and applying for funding to replicate a treatment trial for children with CFS/ME. Dr Emma Anderson, Professor Esther Crawley, Miss Lucy Beasant, Dr Rebecca Barnes, Dr Nicola Mills, June 2018 - November 2019 £265,487 

Medical Research Council (MRC). Pathways to self-harm: Biological mechanisms and genetic contribution. £372,334. 1st June 2017 – 31st May 2019. Alan Emond Co-investigator 

NHS England - (Healthcare Quality Improvement Partnership) Extension to the National Learning disability mortality review programme grant. P. Heslop, PJ Fleming, D. Steer, R. Mallett, D. Needleman, A. Marriott, P S Blair, M. Hoghton,L. Russ. £800,000. 2018-2019

NHS England (Healthcare Quality Improvement Partnership) National Child Mortality Database. K Luyt , V Sleap, J Kurinczuk, J Mooney, PS BlairPJ Fleming. £1,799,404. 2018-2022

NHS Research Endowment Fund. Bowel and bladder dysfunction. C Joinson £43,921. 16th Feb 2017 – 15th Feb 2018. Co-investigator 

NIAAA/NIH (Dr. J Hibbeln, extramural funds). Two small projects: (a) Vitamin B12 intake in pregnancy as an independent factor impacting on offspring neurodevelopmental outcomes; (b) FADS variant: Phenome wide scan using genetic variants that impact essential fatty acid status and function and effects on child neurodevelopmental outcomes. July 2018-June 2020. $70,000. PI: J Golding

NIHR - (RfPB) via Health and Care Research Wales.  Diagnostic accuracy of a clinical prediction tool (BuRN-Tool) to identify maltreatment associated with burns in children. A Emond (co-app ;PI= Kemp, A). £228,000. 2017-19

NIHR Global Health Research Programme, Nepal Injury Research Centre 2017-2020. J Mytton (PI), S Joshi (Nepal), P Pant (UWE), S Manandhar (MIRA, Nepal), C Mikton (UWE), M Ellis (UoB), P Pilkington (UWE), T Deave, G Smart (UWE), J Parking (UWE), D Magnus (UHBT) S Bhatta (UWE), A Banstola (UWE), S Dhungel (Nepal). £1999,313.

NIHR HTA. Co-applicant leading qualitative work and trial management. Blair P, Hay A, Ingram J, Lucas P, Cabral C, Horwood J et al. CHICO: A clinical effectiveness investigation of a multi-faceted intervention (incorporating a prognostic algorithm) to improve management of antibiotics for CHIldren presenting to primary care with acute COugh and respiratory tract infection (CHICO): an efficient cluster RCT informed by a feasibility RCT. £826,831. 2018 – 2021 (30 months)

NIHR Research for Patient Benefit; Co-applicant leading qualitative, PPI and trial management. Evans JE, Ingram JC, Kessler D, Law R et al. ADAGIO: Low intensity interventions for antenatal depression: A feasibility study of an RCT of Interpersonal Counselling compared to Cognitive Behavioural Therapy. £245,201.. 2018 – 2020 (21 months)

NIHR. Evaluating the effect of MenB vaccination on meningococcal carriage. Policy Research Programme. Bristol portion £21,749. A Finn 2018 – 2021.

NIHR. Developing an effective intervention for younger children (5-11 years) with Chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME). Mentor and primary supervisor for A Brigden, award holder. £221,400, Oct 2017 – 2020

The John Templeton Foundation - Transgenerational non-genetic pathways to human development. 2018-2020 (33 months) from 1.1.18 to 30.9.2020. £995,516. PI: J Golding & M Pembrey, with J Henderson, SM Ring, C Williams, A Hall, K Northstone, M Suderman. Ref: 60828

University of Bristol - ESRC Impact Acceleration Account. Joinson, C. Whale, K., & Randall, J. (2017).  September 2017. Co-applicant. £19,860. 

UOB Benjamin Meaker Visiting Professorships from Low & Middle Income Countries (Professor Affette McCaw-Binns, of University of the West Indies, Mona, Jamaica). Investigation of the strategy of mounting an intervention in pregnant women in Jamaica to improve their use of health care services and parenting abilities. 2018.

University of Oxford. Evaluating the effect of MenB vaccination on meningococcal carriage. A Finn £167,124. 2018 – 2021.

Wellcome Trust Institutional Strategic Support Fund (Elizabeth Blackwell Institute TRACK Award) and Enterprise & Impact Development Fund (EIDF). User-centred development of a prototype smartphone application to support the management of daytime urinary incontinence in young people. Joinson C, £42,011 [£24,511 from TRACK and £17,500 from EIDF]. 1st Jan 2017 – 31st Dec 2017.  Principal Investigator 

Wellcome Trust via Elizabeth Backwell Institute - Track Award for the development of an injury prevention photosphere (PI) £15, 400, 2017-2018

2016 - 2017

Medical Research Council (MRC) – Pathways to self harm: Biological mechanisms and genetic contribution.  (Co-Investigator)  Carol Joinson. £372,334. (June 2017 – May 2019)

NHS Research Endowment Fund - Does early frequency and form of stools predict later bowel and bladder dysfunction and their consequences? (Co-Investigator) Carol Joinson. £43,921.00. (February 2017 – February 2018)

NIHR – HTA - CHICO (Children’s Cough). Reducing antibiotic prescribing for children presenting with cough or URTI. (PI) Pete Blair (Co-applicant) Jenny Ingram. £882,400. (2017 – 2020)

NIHR HTA - Antidepressant use during pregnancy: assessing benefits to mothers and long-term neurodevelopmental risks to children using the Clinical Practice Research Datalink. (PI) Dheeraj Raj (Co-Applicant) Alan Emond. £880,000. (2016 – 2019).

The John Templeton Foundation – Transgenerational non-genetic pathways to human development. (PI) Jean Golding and M Pembrey. £995,516. (2017 – 2020)

NIAAA – Two small projects: (a) To assess the relationship between prenatal mercury and academic abilities (including reading and maths) and determine whether there are protective interactions with maternal fish consumption. (b) To determine whether there are protective interactions between prenatal mercury and breast feeding in regard to offspring outcomes including cognitive function and behaviours. (PI) Jean Golding. $35,000. (June 2017 – May 2018)

NIHR Public Health Research Programme - ABA (Assets-based feeding help Before and After birth) study for improving breastfeeding initiation and continuation. (PI) Jenny Ingram (Bristol Site). £328,980. (Nov 2016 – Nov 2018)

NIHR - Multicentre randomised controlled trial in immune thrombocytopenia. (CoA) Rebecca Kandiyali with Jenny Ingram.  £350,000.00 (Jan 2017 - Jan 2020)

NIHR – REPROVIDE. (PI) Gene Feder (Co-Applicant) Rebecca Kandiyali. £3,237,413. (2017 – 2022)

NERC - Gene-environment and gene-gene interactions in myopia. (CoA) Cathy Williams with (PI) Prof J Guggenheim.  £59,823.00 (2016 – 2019)

Elizabeth Blackwell Institute - Elizabeth Blackwell TRACK Award. (PI) Alan Emond (Co-Applicant)  Toity Deave. £14,353 (2017 – 2018)

NIHR Brain Injury Healthcare Technology Cooperative - Feasibility of identifying modifiable factors in non-fatal brain injury in children. (PI) Julie Mytton. £10,000 (2017 -2018)

Bristol Health Partners - On behalf of the Child Injury Health Integration team – patients, families and professionals’ experiences of trauma care pathway services. (PI) Julie Mytton. £6,059 (2017 – 2018)

NIHR - NIHR Nepal Injury Research Centre. (PI) Julie Mytton. £1,999,862 (2017 – 2020)

NIHR – EPPIC (Enhancing Post-Injury Psychological Intervention & Care, Knowledge Mobilisation Research Fellowship. (PI) Kate Beckett. £192,000.00 (2016 – 2019)

2015 - 2016

NIHR - Conservative treatment of appendicitis in children – a randomised controlled trial – CONTRACT (Feasibility Study). (CoA) Esther Crawley with (PI) Nigel Hall.£444,985.63 (2016 – 2019)

NIHR - Health Technology Assessment. Investigating the effectiveness and cost effectiveness of using FITNET to treat paediatric CFS/ME in the UK.  (PI) Esther Crawley,  (CoA) Elise Van de Putte, Sanne Nijhof, Hans Knoop, Gils Bleijenberg, Paul Stallard, David Kessler, Harriet Downing, John Macleod, Simon Price.£999,977.80 (2016-2021)

Action for ME – Severe Paediatric Chronic Fatigue Syndrome/Myalgic Encephalopathy (CFS/ME): British National Surveillance Study  (PI) Esther Crawley.  £6,000.00 (2016 – 2018)     

RNHRD – Severe Paediatric Chronic Fatigue Syndrome/Myalgic Encepahlopathy (CFS/ME): British National Surveillance Study.  (PI) Esther Crawley. £6,000.00 (2016-2018)

Big Lottery Fund via Best Beginnings – Evaluation of a Baby Buddy App (Funded Extension). (PI) Toity Deave. £70,000.00 (2016 – 2018)

Responsible Gambling Trust - A longitudinal study of problem gambling in late adolescence and early adulthood. (PI) Alan Emond.£73,566.00  (2016 – 2019)

Scar Free Foundation - Development of a campaign to prevent hot drink scalds (Safe Tea).  (PI) Alan Emond. £35,000.00 (2016 – 2020)

Action Medical Research: Control of accommodation and eye movements in children with Down's syndrome; the effect of bifocals. PI JM Woodhouse; Co-Apps Prof J Erichsen, C Williams, K Saunders, JA Little, P Watts £169,053. 2015-2018)

NIHR - Cerebral Visual Impairment in primary school age children: prevalence, impact and effectiveness of support. (PI) Cathy Williams. £900,000 (2015 – 2020).

NIHR – HTA. UPSTREAM - Invasive urodynamic testing for male Bladder Outlet Obstruction. PI M Drake (UoB) with co-app PS Blair £1,224,219 (2014 - 2018)

NHS England. (Healthcare Quality Improvement Partnership).  National Learning Disability Mortality Review Programme. PI P.Heslop, with PJ Fleming, D. Steer, R. Mallett, D. Needleman, A. Marriott, P S Blair, M. Hoghton,L. Russ. £2,300,000. 2015-2018

NHS Health Quality Improvement Partnership - National Learning Disability Mortality Review Programme. (PI) Peter Fleming. £2,393,744.00. (2015 – 2018)

Bailey Thomas Charitable Fund - Population-based studies to understand depression, anxiety, suicidality and self-harm as adolescent and early adulthood outcomes of autism. (CoA) Jean Golding, (PI) Dheeraj Rai, with C Magnusson and R Pearson. £74,096.00 (2016-2018)

Other

NIHR – EME. Reducing pathology in Alzheimer’s disease through Angiotensin TaRgeting – The RADAR Trial. Kehoe P (PI). Blair PS (Co-applicant) £2,038,791 (2012-2018)

NIHR – An Investigation of the treatment of paediatric CFS/ME.  (PI) Esther Crawley. £864,736.00. (2014 – 2018)                    

NIHR- Research Design Service – South West. £5,000,000. Ingram J Co-applicant and lead for Bristol site (£120k/year for UoB) 2013 - 2018 (5 years)

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