Diabetes and Metabolism

We are a dynamic research group focused on the causes and prediction of type 1 diabetes in children and adults. Improved prediction of diabetes has been a major achievement in our research and we provide state-of-the-art tests for autoantibodies.

We have many ongoing research projects, including

  • the Bart’s Oxford (BOX) Family study, the largest family study in the world which has been recruiting in the Oxford region of the UK since 1985
  • studies of progression rate to type 1 diabetes
  • the effects of SARS-CoV-2 infection in people with diabetes
  • a focus on why individuals with type 1 diabetes also develop other forms of autoimmunity
  • understanding why children with Down syndrome are at increased risk of autoimmunity

The major questions we are addressing in our research are:

We have a strong commitment to collaborating with diabetes specialists and research groups worldwide, in order to achieve our goal of preventing type 1 diabetes in the future.

photos taken by Tom Farmer

Head of Group

Professor Kathleen Gillespie
Professor of Molecular Medicine
Tel +44(0)117 414 8058


Diabetes and Metabolism
Learning and Research
Second Floor
Southmead Hospital
Bristol BS10 5NB
United Kingdom
Sharon Usher Executive Assistant
Tel: +44 (0)117 414 8044
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