The division of cancer biology is a dynamic integrated group, bringing together the research interests of both clinical and experimental oncologists from a number of different Schools within the Faculty of Medical and Veterinary Sciences, as well as from other Faculties within the University.
Research interests within the Faculty of Medical and Veterinary Sciences include:
The role of the Insulin-like growth factors and their receptors in colorectal tumorigenesis
Dietary factors and Non-steroidal anti-inflammatory agents in the prevention and treatment of colorectal carcinogenesis
The regulation of apoptosis in colorectal epithelial cells
The role of cell adhesion molecules in the development of colorectal cancer
Genetics of childhood tumours
Epigenetic regulation of the Wilm’s tumour suppressor gene
Detection of minimal residual disease in childhood leukaemia
The molecular basis of drug resistance in childhood leukaemia
The treatment and management of paediatric cancers. Human papillomaviruses and cervical cancer
Therapeutic and prophylactic Epstein-Barr virus vaccines
Regulation of gene expression in tumour cells
Microvascular permeability and its relationship to angiogenesis
Regulation of intracellular traffic and the actin cytoskeleton by Rho family GTPases
Proteasomes, intracellular protein and antigen processing.
The teaching staff work within the School of Medical Sciences and the Bristol Teaching Hospitals. The research and teaching of Cancer Biology in Bristol is headed by two professional posts:
Further details are to be found in School web pages. See particularly Cellular and Molecular Medicine and Biochemistry. Click here for details on Bristol Cancer Research. (Use the Biochemistry School Google search to find all links to cancer.)
