Robust evidence is the cornerstone of science and is expertly provided by the suite of facilities integral to the faculty.
Available to both internal and external researchers across the scientific disciplines, as well as international industry, the expertly-run range of facilities make an invaluable contribution to scientific output. This is exemplified by hundreds of seminal publications in high-impact journals that credit the facilities.
A unique fully-integrated suite of electron microscopes, confocal and epifluorescence microscopes allow researchers to explore the fundamental aspects of biology and to dissect the molecular basis of human diseases. The facility supports several important research areas including cell biology, nanotechnology and toxicology. It is also set up for live cell imaging and correlative light and electron microscopy (CLEM).
The facility provides a full range of bespoke proteomics services to medical, veterinary and clinical scientists, allowing the isolation, identification and quantification of proteins in biological samples. The entire process, from sample preparation through to analysis, is carried out in-house. The facility also provides expert advice in experimental design and grant submissions to help researchers secure funding for new initiatives.
The Animal Services Unit provides facilities, services and advice for all scientists within the University who need to carry out research using animals. This work is ethically reviewed, carefully regulated and kept to a minimum, within the overall objectives of advancing knowledge in the areas of biological, biomedical and veterinary sciences. Alternatives to research that involves using animals are always used wherever possible, and all scientists involved in this area are actively involved in the 3Rs (reduction, refinement and replacement).
The Flow Cytometry Facility is comprised of high speed digital benchtop cytometers for analysis and a state of the art Fluorescence Activated Cell Sorter (FASC) for isolating populations of interest from a wide variety of cells or other particles. Aseptically sorted cells can be cultured for downstream studies or used for nucleic acid profiling. From human cells to algae, bacteria and yeast, the flow cytometers provide analyses for academics and industry partners keen to identify and purify subsets of cells to study processes in the human body and in single-celled organisms.
The Histology Services Unit has a range of equipment which staff and students can be trained to use. It also provides a full histology service including wax and frozen sectioning, tissue processing and using a wide range of stains. Immunocytochemistry is also available. Experts are also available to provide help and guidance for histology queries or problems.
Further information available on request
The facility provides expertise and access to the latest genomics and transcriptomics technologies including Illumina next generation sequencing and Affymetrix GeneChip® array analysis.
CRIC Bristol provides key facilities for clinicians and academics to deliver cutting-edge research and improved patient care in areas such as neonatal brain injury, sleep disorders in children, cardiac imaging and diabetes. This includes a Siemens 3T Magnetom MRI Scanner, a Sleep Studies suite and clinical rooms. Uniquely, CRIC Bristol is purpose-built to accommodate studies on babies, children and adults, with provision for both inpatients and healthy volunteers.
The NSQI is an extraordinary interdisciplinary venture bringing together scientists, engineers and medics, to steer innovative collaborations. The purpose-built centre houses laboratories where vibration, temperature, air movement and acoustic noise levels are among the lowest levels ever achieved. The facility has one of the best environments in which to conduct high resolution experiments. Equipment includes Atomic Force Microscopes (AFM), a Dynamic Holographic Assembler (DHA) and both wetlab and cleanroom facilities.
University of Bristol,
Bristol, BS8 1TH, UK
Tel: +44 (0)117 928 9000