Discovery of a druggable pocket in the SARS-CoV-2 Spike protein could stop virus in its tracks21 September 2020A druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells has been discovered by an international team of scientists led by the University of Bristol. The researchers say their findings, published today [21 September] in the journal Science, are a potential 'game changer' in defeating the current pandemic and add that small molecule anti-viral drugs developed to target the pocket they discovered could help eliminate COVID-19.
German Ambassador visits the University 7 September 2020Andreas Michaelis, German Ambassador to the Court of St James's, visited Bristol on Wednesday 2 September accompanied by his wife Frau Heike Michaelis, German Consul General Hans-Guenther Loeffler, and the new Honorary German Consul for Bristol Kai von Pahlen.
Technology takes a step forwards in genetic research11 February 2020New research brings combined computational and laboratory genome engineering a step closer following the design of smaller and smaller genomes, to advance genetic manipulation, using supercomputers by researchers at the University of Bristol.
Catalytic protocells get zingy8 January 2020Artificial cells capable of oxygen gas production and chemical signalling have been prepared using a combination of synthetic and biological catalysts through an international collaboration between the University of Bristol and the University of Padua in Italy.
UK scientists bring innovative vaccine technology to Vietnam27 November 2019World-leading vaccine scientists from the University of Bristol are working with one of Vietnam's major vaccine manufacturers, Vabiotech, to share cutting-edge knowledge that could help prevent future global outbreaks of avian flu and rabies.
Health pioneers celebrated at awards for life-changing chemistry innovations31 October 2019University of Bristol spin-out, Rosa Biotech, was named as one of the most exciting health chemistry innovators in Europe after winning a Royal Society of Chemistry (RSC) Emerging Technologies 2019 award for its biosensing platform that mimics the mammalian olfactory (smelling) system. Rosa was one of two innovations to win the award and a share of £80,000 prize.
University of Bristol spin-out raises £760,000 to commercialise biosensing technology31 October 2019Rosa Biotech, a new University of Bristol spin-out which developed a sensing platform capable of detecting the faint chemical signature given off by chronic diseases has raised £760,000 to commercialise its ground-breaking innovation. The artificial Intelligence (AI)-driven biosensing technology, which mimics mammals’ sense of smell, has significant potential to transform the medical diagnostics and pharmaceuticals industries.
Powerful new synthetic vaccines to combat epidemics25 September 2019A new type of vaccine that can be stored at warmer temperatures, removing the need for refrigeration, has been developed for mosquito-borne virus Chikungunya in a major advance in vaccine technology. The findings, published in Science Advances today [Wednesday 25 September], reveal exceptionally promising results for the Chikungunya vaccine candidate, which has been engineered using a synthetic protein scaffold that could revolutionise the way vaccines are designed, produced and stored.
Scientists hijack bacteria's homing ability3 July 2019In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK (1).
Bristol celebrates awards scoop at science awards7 June 2019Bristol celebrated an awards scoop at the Great West Awards 2019, which honoured the achievements of some of the region's most innovative science and engineering spin-outs and start ups.
Welding with stem cells for next-generation surgical glues23 April 2019Scientists at the University of Bristol have invented a new technology that could lead to the development of a new generation of smart surgical glues and dressings for chronic wounds. The new method, pioneered by Dr Adam Perriman and colleagues, involves re-engineering the membranes of stem cells to effectively “weld” the cells together.
New Max Planck-Bristol Centre for Minimal Biology launched 27 March 2019Building stripped-down versions of life using protocells, genome delivery systems and synthetic cytoskeletons comprise some of the groundbreaking research due to take place at a new Centre launched at the University of Bristol today [Wednesday 27 March]. The Max Planck-Bristol Centre for Minimal Biology, a partnership between the University of Bristol and the Max Planck Society for the Advancement of Science (MPG) in Germany, aims to advance the future of health and medicine by understanding the fundamental nature of life.
University of Bristol recognised in second Life Sciences Sector Deal 12 December 2018Life sciences is a sector that operates at the cutting-edge of technological developments and last week [7 December] the second Life Sciences Sector Deal was announced. The Great West region, including the University of Bristol, was recognised in the report for its flourishing life science industry, due to its collaboration between more established technology and digital businesses.
Creating rings in natural antibiotic synthesis26 November 2018Scientists at the University of Bristol have revealed the secrets of the key ring forming cascade in the biosynthesis of a globally used antibiotic. They hope their findings could lead to the development of antibiotics with improved properties and new biocatalysts for the clean and efficient synthesis of medicinally important molecules.