Publications

2026

Davenport, C. F., A. W. S. Rutjes, S. Mallett, E. Tomlinson, B. Yang, J. Holmes, M. E. Westwood, Y. Takwoingi, J. B. Reitsma, C. Hyde, P. M. M. Bossuyt, J. J. Deeks, M. M. G. Leeflang and P. F. Whiting (2026). "QUADAS-3 Explanation and Elaboration: Guidance for Quality Assessment of Diagnostic Test Accuracy Studies." Ann Intern Med.

Whiting, P. F., E. Tomlinson, A. W. S. Rutjes, C. F. Davenport, B. Yang, M. E. Westwood, Y. Takwoingi, J. B. Reitsma, C. Hyde, P. M. M. Bossuyt, J. J. Deeks, M. M. G. Leeflang and S. Mallett (2026). "QUADAS-3: A Revised Tool for the Quality Assessment of Diagnostic Test Accuracy Studies." Ann Intern Med.

2025

Ades, A. E., A. L. Davies, D. M. Phillippo, H. Pedder, H. Thom, B. Downing, D. M. Caldwell and N. J. Welton (2025). "Treatment recommendations based on network meta-analysis: Rules for risk-averse decision-makers." Res Synth Methods 16(3): 550-568.

Baio G, Thom H, Pechlivanoglou P and (Eds.) (2025). "R for Health Technology Assessment."

Cooper C, D. C. Goncalves-Bradley, C. J. Rose, R. Court, Z. Premji, A. Brown, E. Tomlinson, J. O'Sullivan, J. Carroll, N. Freitag, K. Nothnagel, A. Queder, R. James, C. Lopez Manzano, S. Haftel, S. Gonzalez and U. Schauberger (2025). "Supplementary search methods versus bibliographic database searching to identify studies and study reports." Cochrane Database Syst Rev 11(11): CD015679.

Cooper C, Z. Premji, C. Worsley, E. Tomlinson, S. Dawson and E. Prentice (2025). "A New Process Model of Study Identification Specific to the Identification of Randomised Studies for Systematic Reviews of Medical Interventions." Cochrane Evid Synth Methods 3(3): e70026.

Derezea E, Ades AE, Rogers G, Sutton AJ, Cooper NJ, Hamilton J, Jones HE. ‘Evidence synthesis of diagnostic test accuracy for decision making: Technical Support Document 25’, Available from http://www.nicedsu.org.uk, 2025 

Downing, B. C., N. J. Welton, H. Pedder, I. Mavranezouli, O. Megnin-Viggars and A. E. Ades (2025). "Synthesis of depression outcomes reported on different scales: A comparison of methods for modelling mean differences." Res Synth Methods 16(3): 460-478.

Lopez Manzano C, A. Sadek, C. Cooper, E. Tomlinson, H. Wang, C. Rice, E. Tallantyre, A. Rao-Middleton, P. Whiting and H. Thom. (2025). "Natalizumab and Tyruko (natalizumab biosimilar) for treating highly active relapsing-remitting multiple sclerosis after at least one disease modifying therapy: a systematic review and economic model."  https://www.nice.org.uk/guidance/ta1126

Lunny C, J. P. T. Higgins, I. R. White, S. Dias, B. Hutton, J. M. Wright, A. A. Veroniki, P. F. Whiting and A. C. Tricco (2025). "Risk of Bias in Network Meta-Analysis (RoB NMA) tool." BMJ 388: e079839.

Nevitt S, D. M. Phillippo, R. Hodgson, N. J. Welton and S. Dias (2025). "Application of Multi-level Network Meta-Regression in the NICE Technology Appraisal of Quizartinib for Induction, Consolidation and Maintenance Treatment of Newly Diagnosed FLT3-ITD-Positive Acute Myeloid Leukaemia: An External Assessment Group Perspective." Pharmacoeconomics 43(3): 243-247.

Pedder H, C. Lopez Manzano, L. Claxton, P. Whiting, L. Beggs, A. Sadek, K. Lokuge, E. Tomlinson, Y. Zhang, C. Cooper, R. James, J. Carroll, R. Willans, D. Phillippo, D. Wonderling, A. Dangoor, D. Chauhan, S. O’Brien and N. Welton (2025). "Treatments for metastatic non-small-cell lung cancer: a pathways pilot with systematic review, evidence synthesis, and economic model." (Accepted/In press) NIHR Journals Library. 457 p. (NIHR Open Research)

Perren S, H. Pedder, N. J. Welton and D. M. Phillippo (2025). "Network Meta-Analysis with Class Effects: A Practical Guide and Model Selection Algorithm." Med Decis Making: 272989X251389887.

Phillippo D. (2025). "multinma: Bayesian Network Meta-Analysis of Individual and Aggregate Data. R package version 0.8.1."   Retrieved 03/05/2025, from https://dmphillippo.github.io/multinma/.

Phillippo D, A. Remiro-Azocar, A. Heath, G. Baio, S. Dias, A. E. Ades and N. J. Welton (2025). "Effect modification and non-collapsibility together may lead to conflicting treatment decisions: A review of marginal and conditional estimands and recommendations for decision-making." Res Synth Methods 16(2): 323-349.

Phillippo DM, Sadek A, Pedder H, Welton NJ (2025). Network Meta-Analysis of survival outcomes with non-proportional hazards using flexible M-splines. arXiv preprint arXiv:2509.10383. 

Ren S, S. Ren, N. J. Welton and M. Strong (2025). "Quantitative bias analysis for unmeasured confounding in unanchored population-adjusted indirect comparisons." Res Synth Methods 16(3): 509-527.

Rose C, J. Bidonde, M. Ringsten, J. Glanville, T. Potrebny, C. Cooper, A. E. Muller, H. B. Bergsund, J. F. Meneses-Echavez and R. C. Berg (2025). "Using a Large Language Model (ChatGPT-4o) to Assess the Risk of Bias in Randomized Controlled Trials of Medical Interventions: Interrater Agreement With Human Reviewers." Cochrane Evid Synth Methods 3(5): e70048.

Rose C, J. F. Meneses-Echavez, A. E. Muller, R. C. Berg, T. C. Borge, P. S. J. Jardim and C. Cooper (2025). "Artificial Intelligence and Machine Learning to Improve Evidence Synthesis Production Efficiency: An Observational Study of Resource Use and Time-to-Completion." Cochrane Evid Synth Methods 3(3): e70030.

Tomlinson E, A. Owen-Smith, M. Benavente, C. Cooper, H. E. Jones, M. Ward, J. G. Walker, H. Wang, C. Lopez Manzano, D. Hank, N. J. Welton, M. Leeflang and P. Whiting (2025). "QbTest for ADHD assessment and medication management: a mixed-methods systematic review of impact on clinical outcomes and patient, carer and clinician experiences." BMJ Open 15(4): e095479.

Tomlinson, E., M. Ward, J. Walker, M. Benevente, H. Wang, C. Cooper, H. E. Jones, A. Owen-Smith, C. Lopez Manzano, S. James, D. Hank, N. J. Welton and P. Whiting (2025). "Clinical and cost-effectiveness of technologies for the assessment of attention deficit hyperactivity disorder: a systematic review and economic model." Health Technol Assess 29(58): 1-216.

Zhang X, S. Niyomsri, S. Mandal, H. Mohammed, M. Mindlin, B. Dugbazah, S. Adjei, B. Owoseni, A. Charlett, J. I'Anson, E. Sugars, M. Kliner, T. Mannes, E. Jewitt, L. Gilbert, S. Moazam, C. Dewsnap, D. Phillips, G. Amirthalingam, M. E. Ramsay, P. Vickerman and J. G. Walker (2025). "Cost-effectiveness of vaccination strategies to control future mpox outbreaks in England: a modelling study." Lancet Reg Health Eur 55: 101364.

2024

Ades A, N. J. Welton, S. Dias, D. M. Phillippo and D. M. Caldwell (2024). "Twenty years of network meta-analysis: Continuing controversies and recent developments." Res Synth Methods 15(5): 702-727.

Bullement A, M. Edmondson-Jones, P. Guyot, N. J. Welton, G. Baio, M. Stevenson and N. R. Latimer (2024). "MPES-R: multi-parameter evidence synthesis in R for survival extrapolation—a tutorial." PharmacoEconomics 42(12): 1317-1327.

Carroll J, C. Lopez Manzano, E. Tomlinson, A. Sadek, C. Cooper, H. E. Jones, L. Rowsell, J. Knight, A. Mumford, R. Palmer, W. Hollingworth, N. J. Welton and P. Whiting (2024). "Clinical and cost-effectiveness of clopidogrel resistance genotype testing after ischaemic stroke or transient ischaemic attack: a systematic review and economic model." Health Technol Assess 28(57): 1-194.

Cooper C, A. Booth, K. Husk, R. Lovell, J. Frost, U. Schauberger, N. Britten and R. Garside (2024). "A Tailored Approach: A model for literature searching in complex systematic reviews." Journal of Information Science 50(4): 1030-1062.

Gallardo-Gomez, D., H. Pedder, N. J. Welton, K. Dwan and S. Dias (2024). "Variability in meta-analysis estimates of continuous outcomes using different standardization and scale-specific re-expression methods." J Clin Epidemiol 165: 111213.

Okkaoglu Y, N. J. Welton and H. E. Jones (2024). "Detecting departures from the conditional independence assumption in diagnostic latent class models: a simulation study." BMC Med Res Methodol 24(1): 299.

Phillippo D, S. Dias, A. E. Ades and N. J. Welton. (2024). "Multilevel network meta-regression for general likelihoods: synthesis of individual and aggregate data with applications to survival analysis." https://arxiv.org/abs/2401.12640

Ren S, S. Ren, N. J. Welton and M. Strong (2024). "Advancing unanchored simulated treatment comparisons: A novel implementation and simulation study." Res Synth Methods 15(4): 657-670.

Tomlinson E, M. Ward, C. Cooper, R. James, C. Stokes, S. Begum, J. Watson, A. D. Hay, H. E. Jones, H. Thom and P. Whiting (2024). "Point-of-care tests for urinary tract infections to reduce antimicrobial resistance: a systematic review and conceptual economic model." Health Technol Assess 28(77): 1-109.

Tomlinson, E., C. Cooper, H. E. Jones, C. L. Manzano, R. Palmer, J. Carroll, A. Sadek, N. J. Welton, M. Leeflang and P. Whiting (2024). "Accuracy and technical characteristics of CYP2C19 point of care tests: a systematic review." Pharmacogenomics 25(8-9): 407-423.

Tomlinson, E., H. E. Jones, R. James, C. Cooper, C. Stokes, S. Begum, J. Watson, A. D. Hay, M. Ward, H. Thom and P. Whiting (2024). "Clinical effectiveness of point of care tests for diagnosing urinary tract infection: a systematic review." Clin Microbiol Infect 30(2): 197-205.

Webster, K. E., T. Parkhouse, S. Dawson, H. E. Jones, E. L. Brown, A. D. Hay, P. Whiting, C. Cabral, D. M. Caldwell and J. P. Higgins (2024). "Diagnostic accuracy of point-of-care tests for acute respiratory infection: a systematic review of reviews." Health Technol Assess: 1-75.

2023

Cerullo, E., A. J. Sutton, H. E. Jones, O. Wu, T. J. Quinn and N. J. Cooper (2023). "MetaBayesDTA: codeless Bayesian meta-analysis of test accuracy, with or without a gold standard." BMC Med Res Methodol 23(1): 127.

Cooper C and S. Smith (2023). "The international HTA database returned incomplete search results for NICE technology appraisals: An exploratory study and discussion of the implications." Cochrane Evid Synth Methods 1(10): e12034.

Freeman, S. C., E. Saeedi, J. M. Ordonez-Mena, C. R. Nevill, J. Hartmann-Boyce, D. M. Caldwell, N. J. Welton, N. J. Cooper and A. J. Sutton (2023). "Data visualisation approaches for component network meta-analysis: visualising the data structure." BMC Med Res Methodol 23(1): 208.

Phillippo, D. M., S. Dias, A. E. Ades, M. Belger, A. Brnabic, D. Saure, Y. Schymura and N. J. Welton (2023). "Validating the Assumptions of Population Adjustment: Application of Multilevel Network Meta-regression to a Network of Treatments for Plaque Psoriasis." Med Decis Making 43(1): 53-67.

Riley, R. D., S. Dias, S. Donegan, J. F. Tierney, L. A. Stewart, O. Efthimiou and D. M. Phillippo (2023). "Using individual participant data to improve network meta-analysis projects." BMJ Evid Based Med 28(3): 197-203.

Takwoingi Y, Dendukuri N, Schiller I, Rücker G, Jones HE, Partlett C, Macaskill P (2023). ‘Chapter 10: Undertaking meta-analysis’. In: Deeks JJ, Bossuyt PMM, Leeflang MMG, Takwoingi Y (Eds). Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy, Wiley

Wei, L., D. M. Phillippo, A. Shah, J. G. F. Cleland, J. Lewsey and D. A. McAllister (2023). "Transportability of two heart failure trials to a disease registry using individual patient data." J Clin Epidemiol 162: 160-168.

Whiting P, Marques EMR, Cooper C, Tomlinson E, James R, Welton N, Pedder H, Strawson-Smith T, Gibbs LS, Thom H. (2023) “Olaparib for adjuvant treatment of high-risk HER2-negative, BRCA-positive early breast cancer after chemotherapy: A Single Technology Appraisal.” NICE TA886. 

2022

Adler AI, Slayen S, Stegenga H, Yelan Guo, Diaz R, Welton NJ, Westwood N, Doull I, Crawley C (2022). “NICE guidelines on nivolumab plus ipilimumab for untreated unresectable malignant pleural mesothelioma.” The Lancet Respiratory Medicine Oct;10(10): e92-e93. (Published online 18th August 2022) 

Cerullo, E., H. E. Jones, O. Carter, T. J. Quinn, N. J. Cooper and A. J. Sutton (2022). "Meta-analysis of dichotomous and ordinal tests with an imperfect gold standard." Res Synth Methods 13(5): 595-611.

Daly, C. H., R. Maconachie, A. E. Ades and N. J. Welton (2022). "A non-parametric approach for jointly combining evidence on progression free and overall survival time in network meta-analysis." Res Synth Methods 13(5): 573-584.

Pedder H, S. Dias, M. Boucher, M. Bennetts, D. Mawdsley and N. J. Welton (2022). "Methods to assess evidence consistency in dose-response model based network meta-analysis." Stat Med 41(4): 625-644.

Thom, H. (2022). "Deterministic and Probabilistic Analysis of a Simple Markov Model: How Different Could They Be?" Appl Health Econ Health Policy 20(3): 447-449.

Thom H, J. Leahy and J. P. Jansen (2022). "Network meta-analysis on disconnected evidence networks when only aggregate data are available: modified methods to include disconnected trials and single-arm studies while minimizing bias." Medical Decision Making 42(7): 906-922.

Vervaart M, Strong Mark, Claxton K, Welton Nicky, Wisløff Torbjørn, Aas Eline (2022). “An Efficient Method for Computing Expected Value of Sample Information for Survival Data from an Ongoing Trial.” Medical Decision Making 42(5):612-625