Dr Vito Bruno
Expertise
Cardiac Surgery, Translational Cardiovascular Medicine, Biostatistics, Data Science. Development and clinical application of medical devices in cardiovascular medicine.
Current positions
Honorary Lecturer
Bristol Medical School (THS)
Contact
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Biography
I am a Senior Clinical Research Fellow at Bristol Medical School - Translational Health Science. I have many years of experience in clinical research in cardiovascular medicine. I am a translational research scientist with an interest in the development and clinical application of new medical devices/medications in cardiovascular medicine. I have a large experience in biostatistics and data science and I am currently a Deputy Statistical Editor for the Journal of Thoracic and Cardiovascular Surgery.
Research interests
Translational Cardiovascular Research
As a senior academic fellow in translational health science, my primary interest lies in models of myocardial infarction (MI), myocardial ischemia-reperfusion injury, surgical vascular replacement as well as percutaneous transcatheter placement of intravascular devices. These models are highly relevant to human applications and are used to develop and test new drugs and devices.
Clinical Research
In the clinical research field, I have led and contributed to several retrospectives and prospective studies in the field of Cardiothoracic Surgery, focusing my research on coronary surgery and mitral valve surgery. I have large experience with database validation, advanced statistical analysis, and data presentation.
Publications
Recent publications
01/07/2024Development and translation of thiometallate sulfide donors using a porcine model of coronary occlusion and reperfusion
Redox Biology
Intra-myocardial immunomodulation with human CD16+ monocytes to treat myocardial infarction in pig:
Frontiers in Cardiovascular Medicine
Reporting of surrogate endpoints in randomised controlled trial protocols (SPIRIT-Surrogate): extension checklist with explanation and elaboration
BMJ
Reporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): extension checklist with explanation and elaboration
BMJ
A framework for the definition and interpretation of the use of surrogate endpoints in interventional trials
EClinicalMedicine
Thesis
Related people
Dr Tom Johnson
Associate Professor in Cardiology
Bristol Medical School (THS)
Professor Gianni Angelini
BHF Professor of Cardiac Surgery and Director
Bristol Medical School (THS)
Professor Sarah George
Dean of the Faculty of Health Sciences
Life Sciences Faculty Office
Professor Raimondo Ascione
Professor of Cardiac Surgery and Translational Research and Director of TBRC
Bristol Medical School (THS)