
Professor Richard Apps
PhD, Ph.D.(Bristol)
Current positions
Professor of Neuroscience
School of Physiology, Pharmacology & Neuroscience
Contact
Press and media
Many of our academics speak to the media as experts in their field of research. If you are a journalist, please contact the University’s Media and PR Team:
Research interests
The overall aim of my research is to understand the contributions the mammalian cerebellum makes to the control of voluntary limb movements.
The cerebellum is the largest motor structure within the brain and to succeed in this aim would substantially increase knowledge of the way in which movements are controlled, as well as shed light on the functional organization of a major neural structure and the pathways linking it to other parts of the nervous system.
In particular, the climbing fibre pathways connecting the inferior olive (a brainstem nucleus) to the cerebellum play a vital but enigmatic role in the regulation of movements. In the short to medium term a key aim of my work is to test and refine the hypothesis that these connections provide 'error signals' to the cerebellum during performance of both new and well-rehearsed movements.
Projects and supervisions
Research projects
8051 956414 — CEN - H2020 Marie Sklodowska Curie ITN
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/06/2021 to 31/05/2025
Acetylcholine in cerebellar dependent motor learning
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/01/2019 to 30/06/2023
BBSRC FTMA - Functional neuroanatomical mapping
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
16/07/2018 to 23/11/2018
An Anglo-French-German consortium to understand cerebellar contributions to emotional behaviour
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/05/2018 to 30/06/2019
Anglo-French consortium
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/05/2018 to 30/06/2019
Thesis supervisions
Contributions of the motor cortex and cerebellum during skilled and adapted forelimb reaching
Supervisors
Physiological and behavioural relevance of the cerebellar-periaqueductal grey pathway in fear responses
Supervisors
Acetylcholine in the Interpositus Cerebellar Nuclei
Supervisors
Neural Network Activity during Visuomotor Adaptation
Supervisors
Motor learning in health, ageing and disease
Supervisors
Pharmacological validation and behavioural characterisation of Approach-Avoidance Foraging
Supervisors
Cerebro-cerebellar interactions for temporal information processing
Supervisors
Neural Networks underlying Essential Tremor
Supervisors
Publications
Selected publications
01/09/2009Cerebellar cortical organization: a one-map hypothesis
Nature Reviews Neuroscience
Structural basis of cerebellar microcircuits in the rat
Journal of Neuroscience
Recent publications
06/05/2024Inhibiting cholinergic signalling in the cerebellar interpositus nucleus impairs motor behaviour
European Journal of Neuroscience
Cerebellar Physiology
Trials for Cerebellar Ataxias
Cerebro-cerebellar networks facilitate learning through feedback decoupling
Nature Communications
Dynamic causal modeling reveals increased cerebellar- periaqueductal gray communication during fear extinction
Frontiers
Slower rates of prism adaptation but intact aftereffects in patients with early to mid-stage Parkinson's disease
Neuropsychologia