Dr Paul Chadderton
BA, PhD
Expertise
My goal is to understand how brain circuits combine information from the outside world with internally generated signals to appropriately guide behaviour.
Current positions
Associate Professor in Neurophysiology
School of Physiology, Pharmacology & Neuroscience
Contact
Press and media
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Biography
I apply electrophysiological and imaging techniques including patch clamp and two-photon imaging to study brain circuitry in the intact mammalian brain. I completed my PhD at University College London in the lab of Michael Hausser, followed by postdoctoral research with at UCL and Rutgers University. With the support of an MRC Career Development Award, I established my research group in the Department of Bioengineering at Imperial College London. In 2018, I moved my group to the School of Physiology, Pharmacology and Neuroscience at University of Bristol.
Projects and supervisions
Research projects
BBSRC International Partnership funding - Franchini
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/11/2022 to 31/03/2023
The role of cerebellum in dopamine neuron reward prediction error coding
Principal Investigator
Role
Co-Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/12/2020 to 30/11/2023
The Role of Cerebellar circuitry in movement control and real-time motor learning
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
04/07/2018 to 03/07/2023
Thesis supervisions
Publications
Selected publications
26/07/2022Psilocybin reduces low frequency oscillatory power and neuronal phase-locking in the anterior cingulate cortex of awake rodents.
Scientific Reports
Accounting for uncertainty: inhibition for neural inference in the cerebellum
Proceedings of the Royal Society of London B: Biological Sciences
Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
Nature Communications
Recent publications
30/12/2024Cerebellar-driven cortical dynamics can enable task acquisition, switching and consolidation
Nature Communications
Cerebellar state estimation enables resilient coupling across behavioural domains
Scientific Reports
GlyT2-positive interneurons regulate timing and variability of information transfer in a cerebellar- behavioural loop
Journal of Neuroscience
Cerebro-cerebellar networks facilitate learning through feedback decoupling
Nature Communications
Cerebellar-driven cortical dynamics enable task acquisition, switching and consolidation
Teaching
I contribute to a range of courses on the Neuroscience and Pharmacology programs. These include Pharmacology of Ion Channels and Synaptic Transmission (PICS), Techniques in Neuroscience, and Brain & Behaviour.
