Mr Michael Beer
MBiochem
Current positions
Research Associate
School of Chemistry
Contact
Press and media
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Research interests
My main interests lie in structural biology and biophysics, but I have recently become very interested in molecular dynamics simulations. Overall, the field of enzymology is my wider area of interest.
Publications
Recent publications
08/08/2025Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases
RSC Medicinal Chemistry
Mechanistic basis for inhibition of the extended-spectrum β-lactamase GES-1 by enmetazobactam and tazobactam
FEBS Letters
Dynamical nonequilibrium molecular dynamics simulations reveal allosteric networks, signal transduction mechanisms, and sites associated with drug resistance in biomolecular systems
Molecular Physics
Dynamical responses predict a distal site that modulates activity in an antibiotic resistance enzyme
Chemical Science
Electric Fields Are a Key Determinant of Carbapenemase Activity in Class A β-Lactamases
ACS Catalysis
Thesis
Mechanism, Dynamics and Inhibition of Class A β-Lactamases through Computation and Experiment
Supervisors
Award date
04/02/2025
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