Dr Michael Ambler
FFICM, MA, MBBS, MRCP, PhD
Expertise
Current positions
Consultant Senior Lecturer
School of Physiology, Pharmacology & Neuroscience
Contact
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Research interests
I am interested in the function and dysfunction of the autonomic nervous system during critical illness and how we might modulate this in order to improve outcomes. I study torpor as a model of centrally driven physiological resilience, and am interested in whether inducing synthetic torpor-like states might be protective in models of critical illness.
Publications
Recent publications
20/01/2026Exploring the Requirements of Clinicians for Transparent and Trustworthy Decision Support Systems in Intensive Care: Semistructured Interview Study (Preprint)
Clocks slide rather than freeze during torpor in the mouse
iScience
Estrous cycle modulates fasting-induced torpor propensity via hypothalamic estrogen signalling
Scientific Reports
Synthetic torpor in the rat protects the heart from ischaemia-reperfusion injury
Synthetic torpor in the rat protects the heart from ischaemia-reperfusion injury
Synthetic torpor in the rat recapitulates key features of natural torpor and is cardioprotective
Thesis
Life on hold
Supervisors
Award date
23/03/2021
Related people
Professor Tony Pickering
Professor of Neuroscience and Anaesthesia
School of Physiology, Pharmacology & Neuroscience
Professor Raul Santos-Rodriguez
Professor of Data Science and Intelligent Systems
School of Engineering Mathematics and Technology
Dr Chris McWilliams
Research Fellow
School of Engineering Mathematics and Technology
Miss Megan Elley
Research Associate
School of Physiology, Pharmacology & Neuroscience
Dr Ludovico Taddei
Research Associate
School of Physiology, Pharmacology & Neuroscience