Dr Lucia Marucci
BSc, MSc, PhD
Expertise
Lucia's research aims at quantitively understanding and directly engineering cell functions, with applications spanning biotechnology and healthcare.
Current positions
Associate Professor in Systems and Synthetic Biology
Department of Engineering Mathematics
Contact
Media contact
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Biography
After completing her studies in Mathematics, Lucia started a PhD in Automatic Engineering, focused on the design of synthetic gene network (University of Naples, Italy, PhD award 2010). She then moved to the Centre for Genomic Regulation (Barcelona, Spain) where she was awarded an EMBO Long term fellowship to study gene expression dynamics in pluripotent stem cells.
Lucia moved to Bristol in 2013, where she is currently an Associate Professor in Systems and Synthetic Biology, and an Engineering and Physical Sciences Research Council (EPSRC) Fellow. She co-directs the Bristol BioDesign Institute, a specialised research institute in Synthetic Biology.
Research interests
Projects and supervisions
Research projects
21ENGBIO Reprogramming bacterial cells using whole-cell models
Principal Investigator
Managing organisational unit
Department of Engineering MathematicsDates
15/02/2023 to 14/02/2024
21ENGBIO Reprogramming bacterial cells using whole-cell models
Principal Investigator
Managing organisational unit
Department of Engineering MathematicsDates
15/02/2023 to 14/02/2024
8032 BrisEngBio Pilot Project: Integrating whole-cell models into DBTL cycles: theory to proof-of-concept
Principal Investigator
Managing organisational unit
Department of Engineering MathematicsDates
01/08/2022 to 31/01/2024
Mind the Gap: AI-Augmented Cell-Free Systems for In-Cell Predictions
Principal Investigator
Managing organisational unit
Department of Engineering MathematicsDates
01/06/2022 to 31/05/2023
Mind the Gap: AI-Augmented Cell-Free Systems for In-Cell Predictions
Principal Investigator
Managing organisational unit
Department of Engineering MathematicsDates
01/06/2022 to 31/05/2023
Thesis supervisions
Using and improving whole-cell models to investigate bacterial minimal genomes
Supervisors
A Viral Approach to Translatome Profiling of CA1 Neurons During Associative Recognition Memory Formation
Supervisors
Modelling, control and design of autonomous artificial avatars in human motor coordination task
Supervisors
Multiscale Modelling of Stem Cell Population Dynamics
Supervisors
Dynamics of Biomedical Networks
Supervisors
Minimal Genome Design and Engineering
Supervisors
Investigating the effect of amyloid-beta on hippocampal dynamics in Alzheimer's disease
Supervisors
Identifying and modelling decision making and collective behaviour in multi-agent human and artificial systems
Supervisors
Towards rational genome design
Supervisors
Computational approaches to study human pluripotent stem cell proliferation and fate dynamics<i> in vitro</i>
Supervisors
Publications
Recent publications
16/03/2022Development of a single layer microfluidic device for dynamic stimulation, culture and imaging of mammalian cells
MODEL PREDICTIVE CONTROL OF CANCER CELLULAR DYNAMICS
β-catenin perturbations control differentiation programs in mouse embryonic stem cells
iScience
Control-based continuation: a new approach to prototype synthetic gene networks
A Flow-through Microfluidic Chip for Continuous Dielectrophoretic Separation of Viable and Non-viable Human T-cells
Electrophoresis
Teaching
Lucia has been teaching several units at both the undergraduate and postgraduate levels, including Mathematical Modelling in Physiology and Medicine (a specialised unit covering Systems and Synthetic Biology topics), Engineering Mathematics 1 (a core mathematics unit taught to all engineers), Mathematical and Data Modelling (a project-based unit). She has been teaching within various national and international PhD programs (e.g. EPSRC-funded Synthetic Biology CDT, Oxford).
Related people
Professor Claire Grierson
Professor
School of Biological Sciences
Professor Nigel Savery
Head of School
School of Biochemistry
Mr Joshua Rees-Garbutt
Research Associate
Department of Engineering Mathematics
Dr Francesco Aulicino
Research Associate
School of Biochemistry
Mrs Sandra Montes Olivas
Teaching Associate
Department of Engineering Mathematics