
Dr Justyna Hinchcliffe
BSc, MRes, PhD
Current positions
Senior Research Associate
School of Physiology, Pharmacology & Neuroscience
Contact
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Research interests
My research interests are in the field of behavioural psychopharmacology and animal welfare. I am interested in the links between affective and cognitive processes, especially how learning and memory, decision-making, and reward processing are influenced by the animal’s affective state. My focus is on the neuropsychological mechanisms contributing to the development of the affective biases in the context of the depressive disorder, the neural mechanisms underlying the efficacy of conventional (eg. SSRIs, SNRIs) versus rapid-acting antidepressants (eg. ketamine, psilocybin) utilising translational rodent behavioural models. I am also interested in the development of objective methods for measuring rodents’ affective state and refinement of the techniques used in the behavioural neuroscience to improve animal welfare of the laboratory animals.
Publications
Recent publications
08/05/2026Affective and behavioural interactions between human handlers and laboratory rats
Behavioural Brain Research
Differences in how NMDA antagonists modulate negative affective biases in male rats may serve as a predictor of clinical efficacy in major depressive disorder
Translational Psychiatry
Investigating the effects of different herbal preparations, 5-hydroxytryptophan and involuntary exercise on affective bias modification in male Lister Hooded rats
Behavioural Pharmacology
Rapid-acting antidepressant drugs modulate affective bias in rats
Science Translational Medicine
The Affective Bias Test and Reward Learning Assay
Current Protocols


