
Professor Golam Khandaker
MBBS, MPhil, PhD, FRCPsych
Current positions
Professor of Psychiatry and Immunology and MRC Investigator
Bristol Medical School (PHS)
Contact
Press and media
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Research interests
Golam Khandaker is Professor of Psychiatry at Bristol Medical School, Head of Immunopsychiatry and Experimental Medicine Programme at the MRC Integrative Epidemiology Unit, and Honorary Consultant Psychiatrist at the Avon and Wiltshire Mental Health Parthership NHS Trust. Golam's research focuses on identifying and validating novel immunological mechanisms and potential treatment targets for major psychiatric disorders particularly depression and schizophrenia using epidemiological cohort studies, genetic analysis, and early-phase clinical trials. The key impetus for this work is to move immunotherapies closer to psychiatric practice through innovative translational research. He is also interested in life-course epidemiology of mental disorders, physical and psychiatric multimorbidity especially aetiology, early detection, and prevention of cardiometabolic disease in people with schiozophrenia and depression, and use of routine clinical data for health research.
Projects and supervisions
Research projects
8539 CHECKPOINT: Finding immune and metabolic pathways to severe mental illness
Principal Investigator
Managing organisational unit
Dates
01/04/2024 to 31/03/2029
8539 The South Wales and South West England Mental Health Platform Hub MRC MR/Z503745/1 via Cardiff
Principal Investigator
Managing organisational unit
Dates
01/04/2024 to 31/03/2029
CHECKPOINT: Finding immune and metabolic pathways to severe mental illness
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2024 to 31/03/2029
CHECKPOINT: Finding immune and metabolic pathways to severe mental illness
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2024 to 31/03/2029
The South Wales and South West England Mental Health Platform Hub
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2024 to 31/03/2029
Thesis supervisions
Publications
Recent publications
01/03/2026Inflammatory markers (IL-6 and CRP) in childhood and their association with brain structure and psychotic experiences in adulthood
Brain, Behavior, and Immunity
Interleukin 6 as a Treatment Target for Depression
JAMA Psychiatry
Investigating the Role of Inflammatory Biomarkers in Mediating the Relationship Between Smoking and Depression
Nicotine and Tobacco Research
Neurodevelopmental copy-number variants increase risk of internalizing and cardiometabolic multimorbidity
American Journal of Human Genetics
Prediction models for longitudinal trajectories of depression and anxiety
Journal of Affective Disorders




