Dr Daniel Whitcomb
BSc, MSc(Bristol), PhD
Current positions
Senior Lecturer in Translational Neuroscience
School of Physiology, Pharmacology & Neuroscience
Contact
Press and media
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Projects and supervisions
Research projects
How does ultrasound neuromodulation change neural circuitry?
Principal Investigator
Managing organisational unit
School of Physiology, Pharmacology & NeuroscienceDates
01/01/2026 to 31/12/2028
How does stress regulate tau-associated synaptic function?
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/01/2016 to 31/12/2018
Thesis supervisions
Interplay between synaptic GPCRs in Alzheimer’s Disease
Supervisors
The role of p21-activated kinase in hippocampal synaptic function
Supervisors
The roles of FUS in neurodegenerative disease
Supervisors
Molecular Mechanisms Underlying the Induction of Long-term Potentiation by Transcranial Ultrasound Neuromodulation
Supervisors
Oligodendrocyte distribution in the Hippocampus
Supervisors
The Molecular Mechanisms of Ultrasound Neuromodulation
Supervisors
Neuromodulation and neurotrophic factors
Supervisors
Publications
Selected publications
01/05/2011Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β
Nature Neuroscience
Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization
Cell
Recent publications
01/09/2025Brief transcranial focused ultrasound stimulation causes lasting modifications to the synaptic circuitry of the hippocampus
Brain Stimulation
The effects of 40Hz ultrasound stimulation on neuronal function
The effects of 40Hz ultrasound stimulation on neuronal function
The effects of 40 Hz ultrasound stimulation on neuronal function
AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects human neurons from mitochondrial toxins
Scientific Reports
