Dr Catherine Tooke
PhD, BSc
Current positions
Honorary Research Fellow
School of Cellular and Molecular Medicine
Contact
Press and media
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Publications
Recent publications
22/07/2025Dynamic Behavior and Substrate Interactions of the Polymyxin Resistance Determinant MCR-1 Investigated by Molecular Dynamics Simulations in the Membrane Environment
Journal of Chemical Information and Modeling
Mechanistic Basis for Inhibition of the Extended Spectrum Class A β-Lactamase GES-1 by Tazobactam and Enmetazobactam
FEBS Letters
Dynamical responses predict a distal site that modulates activity in an antibiotic resistance enzyme
Chemical Science
Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics
PLOS Pathogens
Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases
Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases
Thesis
Substrate and Inhibitor Interactions of Class A β-Lactamases
Supervisors
Award date
23/01/2020
Related people
Professor Jim Spencer
Professor of Bacteriology
School of Cellular and Molecular Medicine
Professor Adrian Mulholland
Professor
School of Chemistry
Dr Philip Hinchliffe
Senior Research Associate
School of Cellular and Molecular Medicine
Dr Yuiko Takebayashi
Senior Research Associate
School of Cellular and Molecular Medicine
Mr Michael Beer
Research Associate
School of Chemistry