Mr Andrea Gallio
PhD, MSc, BSc
Expertise
I study how cells balance tetrapyrrole production, breakdown, and transport, and how these processes link to metabolism, with a focus on mitochondrial function and the homeostasis of metal cofactors.
Current positions
Senior Research Associate
School of Chemistry
Contact
Press and media
Many of our academics speak to the media as experts in their field of research. If you are a journalist, please contact the University’s Media and PR Team:
Research interests
I specialise in bioinorganic chemistry and the biology of metals and tetrapyrroles. My research in intracellular heme regulation is distinguished by its interdisciplinary approach, combining live-cell imaging with proteomics, metabolomics, and molecular biology. My work aims to establish quantitative links between heme biosynthesis and degradation, energy metabolism, and the homeostasis of essential metals. My long-term vision is to lead an independent research programme that connects fundamental tetrapyrroles biology (e.g. heme, vitamin B12) with metabolic disorders and iron-related diseases for translational applications in the healthcare sector.
Publications
Recent publications
18/02/2026Monooxygenase Activity of Indoleamine 2,3-Dioxygenase
Journal of the American Chemical Society
Multi-photon fluorescence-lifetime imaging of a genetically-encoded heme sensor
Journal of Inorganic Biochemistry
An extended network for regulation of heme homeostasis in cells
Proceedings of the National Academy of Sciences of the United States of America
In silico prediction of heme binding in proteins
Journal of Biological Chemistry
Heme binding to the SARS-CoV-2 spike glycoprotein
Journal of Biological Chemistry
Thesis
A framework for the investigation of heme homeostasis through genetically encoded heme sensors
Supervisors
Award date
03/10/2023


