Translational Health Sciences

Association between poor sleep quality and an increased risk of developing Alzheimer's, new study finds

New research has shown an association between sleep quality – less than seven hours - and Alzheimer's disease-related pathology in people without cognitive impairment. The study by an international team led by the Pasqual Maragall Foundation research centre, the Barcelonaβeta Brain Research Centre (BBRC), together with researchers from the University of Bristol and North Bristol NHS Trust, is published in the scientific journal Brain Communications today [3 November].

New report finds significantly larger proportion of unexplained infant deaths live in the most deprived neighbourhoods

With the current cost of living crisis, new evidence has found a significantly larger proportion of unexplained infant deaths were among children living in the most deprived neighbourhoods. The new report from England’s National Child Mortality Database (NCMD), led by the University of Bristol, shows 42% of unexplained infant deaths occurred in the most deprived neighbourhoods compared to 8% in the least deprived neighbourhoods.

A new vision for adeno-associated virus delivered gene therapies

An international collaboration of leading groups in gene therapy and vision science have developed an adeno-associated virus (AAV) genome-coupled immunomodulation strategy that helps cloak the AAV virus from unwanted immune responses and offers important insights into ocular inflammation. The research led by Harvard University, Harvard Medical School and including the University of Bristol is published in Science Translational Medicine.