Research

Researchers identify a genetic cause of intellectual disability affecting tens of thousands of people

A neurodevelopmental disorder, caused by mutations in a single gene, affecting tens of thousands of people worldwide, has been identified by researchers. The work, published today [31 May] in Nature Medicine, was conducted by researchers at the Icahn School of Medicine at Mount Sinai, New York in collaboration with colleagues at the University of Bristol, KU Leuven, Belgium; and the NIHR BioResource (currently based at the University of Cambridge).

Cognitive behavioural therapy is effective in reducing depression in people whose symptoms have not responded to treatment with antidepressants

Antidepressants are the most widely used treatment for people with moderate to severe depression. However, up to two thirds of people with depression don’t respond fully to this type of treatment. New findings, published in The Lancet, have shown cognitive behavioural therapy (CBT)*, provided in addition to usual care, can reduce symptoms of depression and help improve patients’ quality of life.