Population Health Sciences

Childhood obesity increases risk of type 1 diabetes

Being overweight in childhood increases the risk of developing type 1 diabetes in later life, according to the findings of a new study that analysed genetic data on over 400,000 individuals. The study, co-led by researchers from the Universities of Bristol and Oxford and published today in Nature Communications, also provides evidence that being overweight over many years from childhood influences the risk of other diseases including asthma, eczema and hypothyroidism.

Results of the largest ever multimorbidity trial in primary care challenge current thinking

In the largest ever trial of an intervention to treat people with multiple long-term conditions (multimorbidity) in primary care, researchers at the Universities of Bristol, Manchester, Dundee and Glasgow found that the patient-centred approach taken improved patients’ experience of their care but did not improve their health-related quality of life. This is a challenge to current thinking on which UK and international guidelines are based.

New TV series co-designed by Bristol mental health expert aims to find out if living a simpler life means a happier and healthier life

Could living a simpler life with no modern comforts, cut off from the modern world be better for us? Bristol mental health researcher, Dr Myles-Jay Linton has contributed to a new Channel 4 series, The Simpler Life, which follows a group of 24 Brits who have given up all their worldly possessions to see whether living a simpler life off grid, without any form of technology, mains electricity or gas, benefits their health and wellbeing.

Discovery of novel brain fear mechanisms offers target for anxiety-reducing drugs

A new target in the brain which underpins the eliciting of anxiety and fear behaviours such as ‘freezing’ has been identified by neuroscientists. The University of Bristol researchers say the discovery of a key pathway in the brain, published in the journal eLife, offers a potential new drug target for treating anxiety and psychological disorders, which affect an estimated 264-million people worldwide.

New evidence on link between obesity and smoking behaviour from genetic data: obese people at higher risk of smoking

A study by the International Agency for Research on Cancer (IARC) provides new evidence that increased weight and obesity may result in increased smoking. The Cancer Research UK (CRUK)-funded study, involving University of Bristol researchers and published today in the British Medical Journal (BMJ), found that increased body mass index (BMI), body fat percentage, and waist circumference were associated both with a higher risk of being a smoker and with greater smoking intensity, measured by the number of cigarettes smoked per day. These results were consistent in both men and women.