Bristol Population Health Science Institute

New study identifies two proteins that may contribute to stroke recurrence

People who experience an arterial ischemic stroke (AIS) or transient ischemic stroke (TIA) are at an increased risk of suffering a second stroke or other major adverse cardiovascular event (MACE), making it critically important to identify risk factors and treatments to prevent these subsequent occurrences. The new study, led by Boston University School of Public Health (BUSPH) and University of Bristol researchers, has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke.

Study of 18 million people finds increased mental illnesses incidence following severe COVID-19, especially in unvaccinated people

A new study that examined health data on 18 million people reveals higher incidence of mental illnesses for up to a year following severe COVID-19 in unvaccinated people. Vaccination appeared to mitigate the adverse effects of COVID-19 on mental illnesses. The University of Bristol-led study, published in JAMA Psychiatry today [21 August], investigated associations of COVID-19 with mental illnesses according to time since diagnosis and vaccination status.

Delaying treatment for localised prostate cancer does not increase mortality risk, trial shows

Active monitoring of prostate cancer has the same high survival rates after 15 years as radiotherapy or surgery, reports the largest study of its kind today. The latest findings from the ProtecT trial, led by the Universities of Bristol and Oxford, are presented today [12 March] at the European Association of Urology (EAU) Congress in Milan and published in the New England Journal of Medicine.

Intervention improves the healthcare response to domestic violence in low- and middle-income countries

Culturally appropriate women-centred interventions can help healthcare systems respond to domestic violence, research has found. HERA (Healthcare Responding to Violence and Abuse) has been co-developing and evaluating a domestic violence and abuse healthcare intervention in low- and middle-income countries for the past five years. This National Institute for Health and Care Research (NIHR) Global Research Group will report their findings, and publish a PolicyBristol report, at a conference in London today [27 November].

Researchers receive share of £7.8 million funding to evaluate digital self-management app for low back pain

Low back pain affects many people in the UK, restricting their daily activities and accounting for 5 per cent of GP appointments. Researchers from the University of Bristol, UWE Bristol and St George’s University Hospital NHS Foundation Trust, in collaboration with the Bristol, North Somerset, South Gloucestershire Integrated Care Board and getUBetter, have secured funding of over £1.3 million to evaluate the implementation of the musculoskeletal self-management app, getUBetter.