Bristol Medical School

Genetic variation that protected against Black Death still helps protect against infection but increases autoimmune disease

The same genetics that helped some of our ancestors fight the plague is still likely to be at work in our bodies today, potentially providing some of the population with extra protection against respiratory diseases such as COVID-19, according to research led by scientists at University of Bristol. However, there is a trade-off, where this same variation is also linked to increased autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.

ProtecT trial receives award for pioneering research demonstrating the safety of active surveillance

A study to find out the best ways of treating prostate cancer has been named the 2024 recipient of the Active Surveillance Patients International (ASPI) Special Award. The ProtecT trial, led by the Universities of Bristol and Oxford, received the award for game-changing research in the development of the active surveillance approach to managing low-risk prostate cancer. Their research has proved active monitoring in patients with lower-risk prostate cancer was as safe as aggressive treatments.

Child asthma deaths linked to air pollution, new report finds

Of the 54 children who died of asthma between 2019 and 2023, more than 90 per cent were exposed to air pollution levels above World Health Organization (WHO) guidelines, according to a new report published today [12 December] by the University of Bristol’s National Child Mortality Database (NCMD) team. The report uses the NCMD’s unique data on all child deaths in England to examine deaths due to asthma or anaphylaxis between April 2019 and March 2023.