Bristol Medical School

Adiposity in childhood affects the risk of breast cancer by changing breast tissue composition, study suggests

Breast cancer is the most common cancer in women worldwide. With rates continuing to rise, there is an urgent need to identify new modifiable breast cancer risk factors. New research led by the University of Bristol suggests that higher adiposity in childhood leads to less dense breast tissue forming, which results in a reduced breast cancer risk. However, further research is needed to understand the mechanism of the overall protective effect of childhood adiposity to identify new targets for intervention and prevention.

Call to reduce repeat 'within-episode' antibiotic prescriptions for respiratory tract infections in primary care

A new study exploring the use of repeat antibiotic prescriptions for the same respiratory tract infection (RTI) episode – known as repeat 'within-episode' prescriptions – in primary care has found high rates of their use in England, despite evidence that they are of little benefit. The study authors, from the Universities of Bristol, Bath, King's College London, and University Medical Center Utrecht, are calling for a reduction in their use and to make them a target for antimicrobial stewardship interventions.