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Co-creating ethical horizons: Public attitudes and regulatory considerations for future cancer nanomedicines in clinical trials

Press release issued: 11 December 2024

The advancement of future cancer nanomedicines, like collective nanosystems, offers a chance to promote responsible governance by anticipating technological developments and addressing ethical issues. Collective nanosystems are large numbers of tiny nano-sized carriers that work together to find and remove cancer cells, drawing inspiration from teams of cooperative robots. Computer models and artificial intelligence can be used to enhance collective nanosystem design, aiming to accelerate targeted treatments and streamline drug development by reducing experimental time.

About this research 

This policy briefing summarises findings from an ongoing PhD project focused on the ethical implementation of collective nanosystems in cancer clinical trials. It seeks to identify regulatory gaps and support ethics committees, regulators, and policymakers in adapting and evolving their ethical frameworks for collective nanosystems in future cancer clinical trials. The PhD used participatory approaches, including interviews, focus groups, and public engagement activities. This involved regulators, policymakers, nanomedicine researchers, healthcare professionals, cancer patients, carers, private and third sector organisations, and interested members of the public. Participatory approaches highlighted the importance of consultation and co-design for the acceptance of future collective nanosystems in cancer trials.

Read more about the briefing on the PolicyBristol webpages

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