Hosted by the Integrative Cancer Epidemiology Programme (ICEP), Progression and Novel Treatments theme
Join Zoom Meeting: https://bristol-ac-uk.zoom.us/j/99470814725?pwd=c2hpSXhwbWlLbFlWU3pEYnJqMlhHdz09
10:30 – Brigid Lynch “Causal pathways from physical inactivity to breast cancer”
This WCRF-funded work was a series of two-part systematic reviews and meta-analyses that synthesised the evidence linking physical inactivity with sex-steroid hormones, insulin and IGF-system signalling, and inflammation; then the same putative pathways with breast cancer risk. There is clear evidence that physical inactivity increases the risk of breast cancer via oestrogens, androgens and sex hormone binding globulin regulation. There is only weak evidence for insulin and IGF-system signalling or inflammatory pathways; in particular there is a dearth of high quality studies on biomarkers of these pathways and breast cancer risk.
11:00 – Jane Blazeby “The ROMIO study: randomised oesophagectomy, minimally invasive or open?”
There will be time for questions and discussion after each presentation.
Brigid Lynch is a cancer epidemiologist whose research focuses on how physical activity and sedentary behaviour are associated with cancer risk, biological mechanisms underlying risk, and health outcomes for cancer survivors. She is the current President of the Australasian Epidemiological Association.
Jane Blazeby FMedSci is Professor of Surgery at the University of Bristol and an Honorary Consultant Surgeon at University Hospitals Bristol NHS Foundation Trust. She studied Medicine at the University of Bristol and undertook higher surgical training in the South West of England