The research groups that make up the Centre for Synaptic Plasticity come from a number of different departments and are independent, each with their own research interests. These range from the investigation of the trafficking and sorting of the various receptor proteins and their interactors that are necessary for synaptic functioning to the involvement of plastic processes in learning and memory as well as in disease. Expertise in generating the tools and reagents necessary for such research is a vital part of the work of The MRC Centre and is often the result of research in other areas of neuroscience and beyond. The broad research interests of each group are indicated here. For simplicity, they have been grouped together to indicate their main focus of research that is relevant to the MRC Centre. Many groups carry out research across the bounadries indicated here and also collaborate closely with each other.