Prenatal and early-life risk factors of ADHD. Using genetically informative designs to adjust for unmeasured confounding
Aleksandra Kanina presenting work by Dr Mina Rosenqvist from Karolinska Institute, Sweden
via Zoom (see link below)
Abstract
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder associated with adverse outcomes throughout life. ADHD has a childhood onset, thus environmental risk exposures are presumed to be early (i.e. prenatal or early-life). However, due to the high heritability of ADHD, it is important to consider the influence of genetic confounding when studying causes of ADHD. In this talk, Dr Rosenqvist will present some findings from studies on prenatal and early-life risk factors of ADHD, where genetically informative designs (such as sibling-comparisons) have been used to adjust for unmeasured genetic and environmental confounding.
Dr Rosenqvist is an assistant professor in psychiatric epidemiology at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet. Her research is mostly focused on studying prenatal and early-life risk factors of neurodevelopmental disorders, in particular ADHD. She has a specific focus on using different genetically informative designs to account for unmeasured genetic and environmental confounding, based on large cohorts and nation-wide population based registers.
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