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Highlighted Publications October-December 2011

Celine S Nicolas; Stephane Peineau; Mascia Amici; Zsolt Csaba; Assia Fafouri; Charlotte Javalet; Valerie J Collett; Lars Hildebrandt; Gillian Seaton; Sun-Lim Choi; Su-Eon Sim; Clarrisa Bradley; Kyungmin Lee; Min Zhuo; Bong-Kiun Kaang; Pierre Gressens; Pascal Dournaud; Stephen M Fitzjohn; Zuner A Bortolotto; Kwangwook Cho; Graham L. Collingridge Neuron, in press

Douglas A. Caruana, E. Clea Warburton and Zafar I. Bashir (2011) Induction of Activity-Dependent LTD Requires Muscarinic Receptor Activation in Medial Prefrontal Cortex J. Neurosci. 31, 18464-18478
Press Release, December 2011

Elianna M. Amin, Sebastian Oltean, Jing Hua, Melissa V.R. Gammons, Maryam Hamdollah-Zadeh, Gavin I. Welsh, Man-Kim Cheung, Lan Ni, Satoru Kase, Emma S. Rennel, Kirsty E. Symonds, Dawid G. Nowak, Brigitte Royer-Pokora, Moin A. Saleem, Masatoshi Hagiwara, Valérie A. Schumacher, Steven J. Harper, David R. Hinton, David O. Bates, Michael R. Ladomery (2011) WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing. Cancer Cell, 20, 768-780
Press Release, December 2011

Jullienne, A, Montagne, A, Orset, C, Lesept, F, Jane, DE, Monaghan, DT, Maubert, E, Vivien, D, Ali, C (2011) Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo. Molecular Neurodegeneration 6:68.

Irvine MW, Costa BM, Dlaboga D, Culley G, Hulse R, Scholefield CL, Atalson P, Fang G, Eaves RJ, Morley R, Mayo-Martin MB, Amici M, Bortolotto ZA, Donaldson L, Collingridge GL, Molnár E, Monaghan DT, Jane DE (2012) Piperazine-2,3-dicarboxylic acids as dual antagonists of NMDA and GluK1-containing kainate receptors. J Med Chem (in press)

Brozzi F, Diraison F, Lajus S, Rajatileka S, Philips T, Regazzi R, Fukuda M, Verkade P, Molnár E, Váradi A (2012) Molecular mechanism of myosin Va recruitment to dense core secretory granules. Traffic 13:54-69.

Fernández-Alacid L, Fajardo-Serrano A, Watanabe M, Shigemoto R, Molnár E, Wickman K, Luján R (2011) Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/KIR3) channel subunits in the brain. Eur J Neurosci 34:1724-1736.

Molnár E (2012) Glutamate receptors. In: Encyclopedia of Signaling Molecules (ed: Choi S), Springer (in press)

Jullienne, A, Montagne, A, Orset, C, Lesept, F, Jane, DE, Monaghan, DT, Maubert, E, Vivien, D, Ali, C (2011) Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo. Molecular Neurodegeneration 6:68.

Clarrisa A Bradley, Stéphane Peineau, Changiz Taghibiglou, Celine S. Nicolas, Daniel J. Whitcomb, Zuner A. Bortolotto,  Bong-Kiun Kaang, Kwangwook Cho, Yu Tian Wang & Graham L. Collingridge Frontiers in Molecular Neuroscience, in press

Costa, BM, Irvine, MW, Fang, G, Eaves, RJ, Mayo-Martin, MB, Laube, B, Jane, DE*, Monaghan, DT* (2012) Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid. Neuropharmacology, (In Press) doi:10.1016/j.neuropharm.2011.11.019

Zsolt Csaba; Stephane Peineau; Pascal Dournaud The JAK/STAT pathway is involved in synaptic plasticity Journal of Molecular Endocrinology, in press

Kate Weatherall, Vincent Seutin, Jean-Francois Liégeois & Neil Marrion (2011) A crucial role of a shared extracellular loop in apamin sensitivity and maintenance of pore shape of SK channels’ Proceedings of National Academy of Sciences 108:18494-18499.
Press Release, November 2011

Brozzi F, Diraison F, Lajus S, Rajatileka S, Philips T, Regazzi R, Fukuda M, Verkade P, Molnar E, Varadi A (2011) Molecular mechanism of myosin Va recruitment to dense core secretory granules. Traffic 12: (in press)

Young AA, Crossman DJ, Ruygrok PN, Cannell MB. (2011) Mapping system for coregistration of cardiac mri and ex vivo tissue sampling. J Magn Reson Imaging. 34:1065-71. doi: 10.1002/jmri.22714. Epub

Harris JR, Helyer RJ, Lloyd E (2011) Using high-fidelity human patient simulators to teach physiology. Med Educ. 45(11):1159-60. doi: 10.1111/j.1365-2923.2011.04105.x

Adeniran I, McPate MJ, Witchel HJ, Hancox JC, Zhang H (2011) Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome. PLoS Computational Biology, (in press).

Emily K. Davies, Yvonne Boyle, Boris A. Chizh, Bridget M. Lumb, Joanna C. Murrell (2011) Ultraviolet B-induced inflammation in the rat: A model of secondary hyperalgesia?   Pain, 15:3 2844-2851

Michal T. Kucewicz, Mark D. Tricklebank, Rafal Bogacz, and Matthew W. Jones (2011) Dysfunctional Prefrontal Cortical Network Activity and Interactions following Cannabinoid Receptor Activation. J. Neurosci.43; 15560-15568
Press Release, October 2011

Luther PK, Winkler H, Taylor K, Zoghbi ME, Craig R, Padrón R, Squire JM & Liu J. (2011) Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle. Proc Natl Acad Sci U S A. 108: 11423-8.

Sood A., Salih S., Roh D., Lacharme-Lora L., Parry M. Hardiman B., Keehan R.,Grummer, R., Winterhager, E., Gokhale. P.J., Andrews P.W., Abbott C., Forbes, K., Westwood M., Aplin J., Ingham. E., Papageorgiou I., Berry, M., Liu, J., Dick, A.D., Garland, R.J., Williams, N., Singh, R., Simon, A.K., Lewis, M., Ham, J., Roger, L., Baird, D.M., Crompton, L.A., Caldwell, M.A., Swalwell, H., Birch-Machin, M., Lopez-Castejon. G., Randall, A., Lin, H., Suleiman, M.S., Evans, W.H., Newson, R., Case, C.P. (2011)  Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness. Nature Nanotechnology (in press).