Maternal smoking during pregnancy and autism: using causal inference methods in a birth cohort study Caramaschi, D., Taylor, A., Richmond, R., Havdahl, K. A., Golding, J., Relton, C., Munafo, M., Davey Smith, G. & Rai, D., 13 Nov 2018, (Accepted/In press) In : Translational Psychiatry.

The effects of prescribing varenicline on two-year health outcomes: an observational cohort study using electronic medical records Davies, N. M., Taylor, G. M. J., Taylor, A. E., Jones, T., Martin, R. M., Munafò, M. R., Windmeijer, F. & Thomas, K. H., 1 Jun 2018, In : Addiction. 113, 6, p.1105-1116

Assessing causal relationships using genetic proxies for exposures: an introduction to Mendelian randomization Katikireddi, S. V., Green, M. J., Taylor, A. E., Davey Smith, G. & Munafò, M. R., 1 Apr 2018, In : Addiction. 113, 4, p.764-774

Collider scope: when selection bias can substantially influence observed associations Munafò, M. R., Tilling, K., Taylor, A. E., Evans, D. M. & Davey Smith, G., 1 Feb 2018, In : International Journal of Epidemiology. 47, 1, p.226-235 , dyx217

Investigating the impact of cigarette smoking behaviours on DNA methylation patterns in adolescence Prince, C., Hammerton, G., Taylor, A., Anderson, E., Timpson, N., Davey Smith, G., Munafo, M., Relton, C. & Richmond, R., 2 Oct 2018, In : Human Molecular Genetics.

Association of alcohol consumption with allergic disease and asthma: a multicenter Mendelian Randomization analysis Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B., Shabanzadeh, D. M., Gonzalez-Quintela, A., Power, C., Hyppönen, E., Kuh, D., Hardy, R., Meitinger, T., Jukema, J. W., Völker, U., Nauck, M., Völzke, H., Friedrich, N., Bonten, T. N., Noordam, R., Mook-Kanamori, D. O., Tolstrup, J. S., Taube, C., Peters, A., Grallert, H., Strauch, K., Schulz, H., Grarup, N., Hansen, T., Pedersen, O., Burgess, S., Munafò, M. R. & Linneberg, A., 28 Aug 2018, (Accepted/In press) In : Addiction.

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, T., Pedersen, O., Jørgensen, T., Paternoster, L., Munafò, M., Grarup, N. & Linneberg, A., 1 Jan 2018, In : Allergy. 73, 1, p.153-164

Associations of coffee genetic risk scores with consumption of coffee, tea and other beverages in the UK Biobank Taylor, A. E., Davey Smith, G. & Munafò, M. R., Jan 2018, In : Addiction. 113, 1, p.148-157

The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children Taylor, A., Jones, H., Sallis, H., Euesden, J., Davies, N., Zammit, S., Lawlor, D., Munafo, M., Davey Smith, G. & Tilling, K., 18 Mar 2018, (Accepted/In press) In : International Journal of Epidemiology.

Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children Taylor, A., Jones, H., Sallis, H., Davey Smith, G., Lawlor, D., Davies, N., Stergiakouli, E., Munafo, M., Euesden, J., Tilling, K. & Zammit, S., 23 May 2018, In : International Journal of Epidemiology

The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study Taylor, A., Richmond, R., Palviainen, T., Loukola, A., Wootton, R., Kaprio, J., Relton, C., Davey Smith, G. & Munafo, M., 30 Nov 2018, (Accepted/In press) In : Human Molecular Genetics.

Is smoking heaviness causally associated with alcohol use? A Mendelian randomization study in four European cohorts Taylor, M., Rode, L., Bjorngaard, J., Taylor, A., Bojensen, S., Asvold, B., Gabrielsen, M., Lewis, G., Nordestgaard, B., Romundstad, P., Hickman, M. & Munafo, M., 2 Mar 2018, In : International Journal of Epidemiology.

Investigating genetic correlations and causal effects between caffeine consumption and sleep behaviours  Treur, J. L., Gibson, M., Taylor, A. E., Rogers, P. J. & Munafò, M. R., 1 Oct 2018, In : Journal of Sleep Research. 27, 5, , e12695

Evidence for genetic correlations and bidirectional, causal effects between smoking and sleep behaviours Treur, J., Munafo, M., Taylor, A. & Gibson, M., 20 Oct 2018, (Accepted/In press) In : Nicotine and Tobacco Research.

Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study Wootton, R., Lawn, R., Millard, L., Davies, N., Taylor, A., Munafo, M., Timpson, N., Davis, O. S. P., Davey Smith, G. & Haworth, C., 25 Sep 2018, In : BMJ. 362, , k3788

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants Zhou, A., Taylor, A. E., Karhunen, V., Zhan, Y., Rovio, S. P., Lahti, J., Sjögren, P., Byberg, L., Lyall, D. M., Auvinen, J., Lehtimäki, T., Kähönen, M., Hutri-Kähönen, N., Perälä, M. M., Michaëlsson, K., Mahajan, A., Lind, L., Power, C., Eriksson, J. G., Raitakari, O. T., Hägg, S., Pedersen, N. L., Veijola, J., Järvelin, M. R., Munafò, M. R., Ingelsson, E., Llewellyn, D. J. & Hyppönen, E., 14 May 2018, In : Scientific Reports. 8, , 7526

Early life adiposity and telomere length across the life course: a systematic review and meta-analysis Anna L Guyatt, Santiago Rodriguez, Tom R Gaunt, Abigail Fraser, Emma L Anderson, Wellcome Open Research

Association of copy number variation across the genome with neuropsychiatric traits in the general population Louise Wain, Nick Shrine, Anna Guyatt, Vicki Jackson, A Mesut Erzurumluoglu, Chiara Batini, Nicola Reeve, Brian Hobbs, Michael Cho, David Strachan, Andrew Morris, Ian Hall, Martin Tobin, American journal of medical genetics, July 2018.

A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts Anna Louise Guyatt, Rebecca R Brennan, Kimberley Burrows, Philip AI Guthrie, Raimondo Ascione, Susan M Ring, Tom R Gaunt, Angela Pyle, Heather J Cordell, Deborah A Lawlor, Patrick Chinnery, Gavin Hudson, Santiago Rodriguez, Human Genomics, January 2019. 

Physical activity producing low, but not medium or higher, vertical impacts is inversely related to BMI in older adults: findings from a multi cohort study Elhakeem, A., Hannam, K., Deere, K., Hartley, A., Clark, E., Moss, C., Edwards, M., Dennison, E., Gaysin, T., Kuh, D., Wong, A., Cooper, C., Cooper, R. & Tobias, J., 17 Apr 2018, In : Journals of Gerontology, Series A. 73, 5, p.643-651

Lean mass and lower limb muscle function in relation to hip strength, geometry and fracture risk indices in community-dwelling older women Elhakeem, A., Hartley, A., Luo, Y., Goertzen, A., Hannam, K., Clark, E., Leslie, W. & Tobias, J., 29 Nov 2018, (Accepted/In press) In : Osteoporosis International.

Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved from Day-to-day Physical Activity Hartley, A., Gregson, C. L., Hannam, K., Deere, K. C., Clark, E. M. & Tobias, J. H., 17 Apr 2018, In : Journals of Gerontology, Series A. 73, 5, p.652-659 , glx223

Causal inference in cancer epidemiology: What is the role of mendelian randomization? Yarmolinsky, J., Wade, K. H., Richmond, R. C., Langdon, R. J., Bull, C. J., Tilling, K. M., Relton, C. L., Lewis, S. J., Smith, G. D. & Martin, R. M., 1 Sep 2018, In : Cancer Epidemiology, Biomarkers and Prevention. 27, 9, p.995-1010

Health impacts of parental migration on left-behind children and adolescents: a systematic review and meta-analysis Fellmeth, G., Rose-Clark, K., Zhao, C., Laura B., Zheng, Y., Massazza, A., Sonmez, H., Eder, B., Blewitt, A., Lertgrai,W., Orcutt, M., Ricci, K., Mohamed-Ahmed, O., Burns, R., Knipe, D., Hargreaves, S., Hesketh, T., Opondo, C. & Devakumar, D., 9 Oct 2018

 

Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa Ingram, J., Jenkins-Jones, S., Knipe, D., Morgan, C., Cannings-John, R. & Piguet, V., 1 Apr 2018, In : British Journal of Dermatology. 178, 4, p.917-924

Medical, dentistry and veterinary student mental health in England: A cross-sectional online survey Knipe, D., Dymock, D., Moran, P. & Gunnell, D., 24 Sep 2018, (Accepted/In press) In : BJPsych Open

Attempted suicide in Sri Lanka – An epidemiological study of household and community factors Knipe, D., Gunnell, D., Pearson, M., Jayamanne, S., Pieris, R., Priyadarshana, C., Weerasinghe, M., Hawton, K., Konradsen, F., Eddleston, M. & Metcalfe, C., 1 May 2018, In : Journal of Affective Disorders. 232, p.177-184

New drug controls and reduced hospital presentations due to novel psychoactive substances in Edinburgh Pettie, J., Burt, A., Knipe, D. W., Torrance, H., Dow, M., Osinski, K., Greig, R., Sabatini, D., Easterford, K., Dear, J. & Eddleston, M., 1 Oct 2018, In : British Journal of Clinical Pharmacology. 84, 10, p.2303-2310

Accuracy of risk scales for predicting repeat self-harm and suicide: a multicentre, population-level cohort study using routine clinical data Steeg, S., Quinlivan, L., Nowland, R., Carroll, R., Casey, D., Clements, C., Cooper, J., Davies, L., Knipe, D., Ness, J., O'Connor, R. C., Hawton, K., Gunnell, D. & Kapur, N., 25 Apr 2018, In : BMC Psychiatry. 18, 1, , 113

Identifying Critical Points of Trajectories of Depressive Symptoms from Childhood to Young Adulthood Kwong, A., Manley, D., Timpson, N., Pearson, R., Heron, J., Sallis, H., Stergiakouli, E., Davis, O. S. P.& Leckie, G., 7 Dec 2018, (Accepted/In press) In : Journal of Youth and Adolescence.

Investigating possible causal effects of externalizing behaviors on tobacco initiation: a Mendelian randomization analysis Fluharty, M. E., Sallis, H. & Munafò, M. R., 1 Oct 2018, In : Drug and Alcohol Dependence. 191, p.338-342

Cigarette smoking and personality: interrogating causality using Mendelian randomization Sallis, H., Davey Smith, G. & Munafo, M., 25 Sep 2018, (Accepted/In press) In : Psychological Medicine

Genetics of biologically based psychological differences Sallis, H., Smith, G. D. & Munafò, M. R., 19 Apr 2018, In : Philosophical Transactions B: Biological Sciences. 373, 1744, , 20170162

Interaction between cannabis consumption and childhood abuse in psychotic disorders: preliminary findings on the role of different patterns of cannabis use Sideli, L., Fisher, H. L., Murray, R. M., Sallis, H., Russo, M., Stilo, S. A., Paparelli, A., Wiffen, B. D. R., O'Connor, J. A., Pintore, S., Ferraro, L., La Cascia, C., La Barbera, D., Morgan, C. & Di Forti, M., Apr 2018, In : Early Intervention in Psychiatry. 12, 2, p.135-142

The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children Taylor, A., Jones, H., Sallis, H., Euesden, J., Davies, N., Zammit, S., Lawlor, D., Munafo, M., Davey Smith, G. & Tilling, K., 18 Mar 2018, (Accepted/In press) In : International Journal of Epidemiology.

Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children Taylor, A., Jones, H., Sallis, H., Davey Smith, G., Lawlor, D., Davies, N., Stergiakouli, E., Munafo, M., Euesden, J., Tilling, K. & Zammit, S., 23 May 2018, In : International Journal of Epidemiology. , dyy060

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects Carolina Medina-Gomez, John P Kemp, Katerina Trajanoska, Jian’an Luan, Alessandra Chesi, Tarunveer S Ahluwalia, Dennis O Mook-Kanamori, Annelies Ham, Fernando P Hartwig, Daniel S Evans, Raimo Joro, Ivana Nedeljkovic, Hou-Feng Zheng, Kun Zhu, Mustafa Atalay, Ching-Ti Liu, Maria Nethander, Linda Broer, Gudmar Porleifsson, Benjamin H Mullin, Samuel K Handelman, Mike A Nalls, Leon E Jessen, Denise HM Heppe, J Brent Richards, Carol Wang, Bo Chawes, Katharina E Schraut, Najaf Amin, Nick Wareham, David Karasik, Nathalie Van der Velde, M Arfan Ikram, Babette S Zemel, Yanhua Zhou, Christian J Carlsson, Yongmei Liu, Fiona E McGuigan, Cindy G Boer, Klaus Bønnelykke, Stuart H Ralston, John A Robbins, John P Walsh, M Carola Zillikens, Claudia Langenberg, Ruifang Li-Gao, Frances MK Williams, Tamara B Harris, Kristina Akesson, Rebecca D Jackson, Gunnar Sigurdsson, Martin den Heijer, Bram CJ van der Eerden, Jeroen van de Peppel, Timothy D Spector, Craig Pennell, Bernardo L Horta, Janine F Felix, Jing Hua Zhao, Scott G Wilson, Renée de Mutsert, Hans Bisgaard, Unnur Styrkársdóttir, Vincent W Jaddoe, Eric Orwoll, Timo A Lakka, Robert Scott, Struan FA Grant, Mattias Lorentzon, Cornelia M van Duijn, James F Wilson, Kari Stefansson, Bruce M Psaty, Douglas P Kiel, Claes Ohlsson, Evangelia Ntzani, Andre J van Wijnen, Vincenzo Forgetta, Mohsen Ghanbari, John G Logan, Graham R Williams, JH Duncan Bassett, Peter I Croucher, Evangelos Evangelou, Andre G Uitterlinden, Cheryl L Ackert-Bicknell, Jonathan H Tobias, David M Evans, Fernando Rivadeneira, AJHG, Volume 102, Issue 1, 4th January 2018.

The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization studyJIE ZHENG, Marie-Jo Brion, John Kemp, Nicole Warrington, Carolina Borges, Gibran Hemani, Thomas Richardson, Zhen Qiao, Philip Haycock, Mika Ala-Korpela, George Davey Smith, Jonathan Tobias, David Evans, Journal of Bone and Mineral Research, 5th December 2018

Machine Learning to Predict Osteoporotic Fracture Risk from GenotypesVincenzo Forgetta, Julyan Keller-Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John Kemp, John A Morris, John A Kanis, Douglas P Kiel, Eugene V McCloskey, Fernando Rivadeneira, Helena Johannson, Nicholas Harvey, Cyrus Cooper, David M Evans, Joelle Pineau, William D Leslie, Celia MT Greenwood, J Brent Richards, 2018

An Atlas of Human and Murine Genetic Influences on OsteoporosisJohn A Morris, John P Kemp, Scott E Youlten, Laetitia Laurent, John G Logan, Ryan Chai, Nicholas A Vulpescu, Vincenzo Forgetta, Aaron Kleinman, Sindhu Mohanty, C Marcelo Sergio, Julian Quinn, Loan Nguyen-Yamamoto, Aimee-Lee Luco, Jinchu Vijay, Marie-Michelle Simon, Albena Pramatarova, Carolina Medina-Gomez, Katerina Trajanoska, Elena J Ghirardello, Natalie C Butterfield, Katharine F Curry, Victoria D Leitch, Penny C Sparkes, Anne-Tounsia Adoum, Naila S Mannan, Davide Komla-Ebri, Andrea S Pollard, Hannah F Dewhurst, Thomas Hassell, Michael-John G Beltejar, Douglas J Adams, Suzanne M Vaillancourt, Stephen Kaptoge, Paul Baldock, Cyrus Cooper, Jonathan Reeve, Evangelia Ntzani, Evangelos Evangelou, Claes Ohlsson, David Karasik, Fernando Rivadeneira, Douglas P Kiel, Jonathan H Tobias, Celia L Gregson, Nicholas C Harvey, Elin Grundberg, David Goltzman, David J Adams, Christopher J Lelliott, David A Hinds, Cheryl L Ackert-Bicknell, Yi-Hsiang Hsu, Matthew T Maurano, Peter I Croucher, Graham R Williams, JH Duncan Bassett, David M Evans, J Brent Richards, Nature Genetics, February 2019.

Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study Bell, J., Carslake, D., Wade, K., Richmond, R., Langdon, R., Vincent, E., Holmes, M., Timpson, N. & Davey Smith, G., 28 Aug 2018, In : PLoS Medicine. 15, 8, , e1002641

Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans Cho, Y., Kwak, S., Lewis, S. J., Wade, K. H., Relton, C. L., Smith, G. D. & Shin, M-J., 11 Jan 2018, In : Scientific Reports. 8, 1, , 458

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference Corbin, L. J., Tan, V. Y., Hughes, D. A., Wade, K. H., Paul, D. S., Tansey, K. E., Butcher, F., Dudbridge, F., Howson, J. M., Jallow, M. W., John, C., Kingston, N., Lindgren, C. M., O'Donavan, M., O'Rahilly, S., Owen, M. J., Palmer, C. N. A., Pearson, E. R., Scott, R. A., Van Heel, D. A., Whittaker, J., Frayling, T., Tobin, M. D., Wain, L. V., Smith, G. D., Evans, D. M., Karpe, F., McCarthy, M. I., Danesh, J., Franks, P. W. & Timpson, N. J., 19 Feb 2018, In : Nature Communications. 9, 1, , 711

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis Haworth, S., Mitchell, R., Corbin, L., Wade, K., Dudding, T., Budu-Aggrey, A., Carslake, D., Hemani, G., Paternoster, L., Davey Smith, G., Davies, N., Lawson, D. & Timpson, N., 9 Nov 2018, (Accepted/In press) In : Nature Communications.

The MR-Base platform supports systematic causal inference across the human phenome Hemani, G., Zheng, J., Elsworth, B., Wade, K., Haberland, V., Baird, D., Laurin, C., Burgess, S., Bowden, J., Langdon, R., Tan, V., Yarmolinsky, J., Shihab, H., Timpson, N., Evans, D., Relton, C., Martin, R., Davey Smith, G., Gaunt, T. & Haycock, P., 30 May 2018, In : eLife. 7, , e34408

Epigenetic gestational age acceleration: A prospective cohort study investigating associations with familial, sociodemographic and birth characteristics Khouja, J. N., Simpkin, A. J., O'Keeffe, L. M., Wade, K. H., Houtepen, L. C., Relton, C. L., Suderman, M. & Howe, L. D., 27 Jun 2018, In : Clinical Epigenetics. 10, , 86

Associations of Y chromosomal haplogroups with cardiometabolic risk factors and subclinical vascular measures in males during childhood and adolescence O'Keeffe, L. M., Howe, L., Fraser, A., Hughes, A. D., Wade, K., Anderson, E., Lawlor, D., Erzurumluoglu, M., Davey Smith, G., Rodriguez, S. & Stergiakouli, E., Jul 2018, In : Atherosclerosis. 274, p.94-103

Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses Wade, K., Chiesa, S., Hughes, A. D., Chaturvedi, N., Charakida, M., Rapala, A., Muthurangu, V., Khan, T. A., Finer, N., Sattar, N., Howe, L., Fraser, A., Lawlor, D., Davey Smith, G., Deanfield, J. & Timpson, N., 30 Jul 2018, In : Circulation. 138, 20,

BMI and Mortality in UK Biobank: Revised Estimates Using Mendelian Randomization Wade, K., Carslake, D., Sattar, N., Davey Smith, G. & Timpson, N., Nov 2018, In : Obesity. 26, 11, p.1796-1806

Physical activity and longevity: how to move closer to causal Wade, K., Richmond, R. & Davey Smith, G., 15 Mar 2018, In : British Journal of Sports Medicine. 52, 14, p.890-891

Causal inference in cancer epidemiology: What is the role of mendelian randomization? Yarmolinsky, J., Wade, K. H., Richmond, R. C., Langdon, R. J., Bull, C. J., Tilling, K. M., Relton, C. L., Lewis, S. J., Smith, G. D. & Martin, R. M., 1 Sep 2018, In : Cancer Epidemiology, Biomarkers and Prevention. 27, 9, p.995-1010

Cardiometabolic phenotypes and mitochondrial DNA copy number in two cohorts of UK women Guyatt, A. L., Burrows, K., Guthrie, P. A. I., Ring, S., McArdle, W., Day, I. N. M., Ascione, R., Lawlor, D. A., Gaunt, T. R. & Rodriguez, S., 1 Mar 2018, In : Mitochondrion. 39, p.9-19

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts Sharp, G., Arathimos, R., Reese, S., Page, C., Felix, J. F., Kupers, L., Rifas-Shiman, S. L., Liu, C., Burrows, K., Zhao, S., Magnus, M., Duijts, L., Corpeleijn, E., DeMeo, DL., Litonjua, A., Baccarelli, AA., Hivert, M-F., Oken, E., Snieder, H., Jaddoe, V. W. V., Nystad, W., London, S., Relton, C. & Zuccolo, L., Jan 2018, In : Epigenomics.

Using SITAR (SuperImposition by Translation and Rotation) to estimate age at peak height velocity in Avon Longitudinal Study of Parents and Children Frysz, M., Howe, L., Tobias, J. & Paternoster, L., 3 Oct 2018, In : Wellcome Open Research. 3, , 90

The Roles of 27 Genera of Human Gut Microbiota in Ischemic Heart Disease, Type 2 Diabetes Mellitus, and Their Risk Factors: A Mendelian Randomization Study Yang, Q., 1 Sep 2018, In : American Journal of Epidemiology. 187, 9, p.1916-1922 , kwy096

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study Adams, C., Richmond, R. C., Santos Ferreira, D. L. D., Spiller, W., Tan, V. Y., Zheng, J., Wurtz, P., Donovan, J. L., Hamdy, F. C., Neal, D. E., Lane, J. A., Davey Smith, G., Relton, C. L., Eeles, R. A., Henderson, B. E., Haiman, C. A., Kote-Jarai, Z., Schumacher, F. R., Amin Al Olama, A., Benlloch, S., Muir, K., Berndt, S. I., Conti, D. V., Wiklund, F., Chanock, S. J., Gapstur, S. M., Stevens, V. L., Tangen, C. M., Batra, J., Clements, J. A., Grönberg, H., Pashayan, N., Schleutker, J., Albanes, D., Wolk, A., West, C. M. L., Mucci, L. A., Cancel-Tassin, G., Koutros, S., Sørensen, K. D., Maehle, L., Travis, R. C., Hamilton, R., Ingles, S. A., Rosenstein, B. S., Lu, Y-J., Giles, G. G., Kibel, A. S., Vega, A., Kogevinas, M., Penney, K. L., Park, J. Y., Stanford, J. L., Cybulski, C., Nordestgaard, B. G., Brenner, H., Maier, C., Kim, J., John, E. M., Teixeira, M. R., Neuhausen, S. L., DeRuyck, K., Razack, A., Newcomb, L. F., Lessel, D., Kaneva, R. P., Usmani, N., Claessens, F., Townsend, P., Gago Dominguez, M., Roobol, M. J., Menegaux, F., Khaw, K-T., Cannon-Albright, L. A., Pandha, H., Thibodeau, S. N. & Martin, R. M., 23 Oct 2018, In : Cancer Epidemiology, Biomarkers and Prevention.

DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival Ambatipudi, S., Langdon, R., Richmond, R. C., Suderman, M., Koestler, D. C., Kelsey, K. T., Kazmi, N., Penfold, C., Ho, K. M., McArdle, W., Ring, S. M., Pring, M., Waterboer, T., Pawlita, M., Gaunt, T. R., Davey Smith, G., Thomas, S., Ness, A. R. & Relton, C. L., 1 Oct 2018, In : Oral Oncology. 85, p.87-94

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma Arathimos, R., Granell, R., Haycock, P., Richmond, R., Yarmolinsky, J., Relton, C. & Tilling, K., 26 Nov 2018, (Accepted/In press) In : Thorax.

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J. J., Allard, C., Barton, S. J., Espinosa, A., Marsh, J. A., Potter, C., Zhang, G., Ang, W., Berry, D. J., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, Ø., Hocher, B., Hofman, A., Inskip, H. M., Jones, S. E., Kogevinas, M., Lind, P. A., Marullo, L., Medland, S. E., Murray, A., Murray, J. C., Njølstad, P. L. R., Nohr, E. A., Reichetzeder, C., Ring, S. M., Ruth, K. S., Relton, C. L., Sørensen, T. I. A., Evans, D. M., Lawlor, D. A., Freathy, R. M. & Early Growth Genetics (EGG) Consortium, 15 Feb 2018, In : Human Molecular Genetics. 27, 4, p.742-756 , ddx429

Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study Bell, J., Carslake, D., Wade, K., Richmond, R., Langdon, R., Vincent, E., Holmes, M., Timpson, N. & Davey Smith, G., 28 Aug 2018, In : PLoS Medicine. 15, 8, , e1002641

Maternal smoking during pregnancy and autism: using causal inference methods in a birth cohort study Caramaschi, D., Taylor, A., Richmond, R., Havdahl, K. A., Golding, J., Relton, C., Munafo, M., Davey Smith, G. & Rai, D., 13 Nov 2018, (Accepted/In press) In : Translational Psychiatry.

Testing the validity of value-added measures of educational progress with genetic data Morris, T., Davies, N., Dorling, D., Richmond, R. & Davey Smith, G., 1 Oct 2018, In : British Educational Research Journal. 44, 5, p.725-747

Investigating the impact of cigarette smoking behaviours on DNA methylation patterns in adolescence Prince, C., Hammerton, G., Taylor, A., Anderson, E., Timpson, N., Davey Smith, G., Munafo, M., Relton, C. & Richmond, R., 2 Oct 2018, In : Human Molecular Genetics.

The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen folic acid supplementation trial (AFAST) Richmond, R., Sharp, G., Herbert, G., Atkinson, C., Taylor, C., Bhattachrya, S., Campbell, D., Hall, M., Kazmi, N., Gaunt, T., McArdle, W., Ring, S., Davey Smith, G., Ness, A. R. & Relton, C., 12 Mar 2018, In : International Journal of Epidemiology. 47, 3

DNA methylation as a marker for prenatal smoke exposure in adults Richmond, R., Suderman, M., Langdon, R., Relton, C. & Davey Smith, G., 31 May 2018, In : International Journal of Epidemiology.

The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study Taylor, A., Richmond, R., Palviainen, T., Loukola, A., Wootton, R., Kaprio, J., Relton, C., Davey Smith, G. & Munafo, M., 30 Nov 2018, (Accepted/In press) In : Human Molecular Genetics.

Physical activity and longevity: how to move closer to causal Wade, K., Richmond, R. & Davey Smith, G., 15 Mar 2018, In : British Journal of Sports Medicine. 52, 14, p.890-891

Causal inference in cancer epidemiology: What is the role of mendelian randomization? Yarmolinsky, J., Wade, K. H., Richmond, R. C., Langdon, R. J., Bull, C. J., Tilling, K. M., Relton, C. L., Lewis, S. J., Smith, G. D. & Martin, R. M., 1 Sep 2018, In : Cancer Epidemiology, Biomarkers and Prevention. 27, 9, p.995-1010

Tobacco smoking and alcohol drinking at diagnosis of head and neck cancer and all-cause mortality: Results from head and neck 5000, a prospective observational cohort of people with head and neck cancer Beynon, R. A., Lang, S., Schimansky, S., Penfold, C. M., Waylen, A., Thomas, S. J., Pawlita, M., Tim, W., Martin, R. M., May, M. & Ness, A. R., Sep 2018, In : International Journal of Cancer. 143, 5, p.1114-1127

Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial Beynon, R., Richmond, R., Dos Santos Ferreira, D., Ness, A. R., May, M., Davey Smith, G., Vincent, E., Adams, C., Ala-Korpela, M., Wurtz, P., Soidinsalo, S., Metcalfe, C., Donovan, J., The Protect Study, G., The PRACTICAL, C., Lane, J. A. & Martin, R., 24 Sep 2018, (Accepted/In press) In : International Journal of Cancer.

Health behaviours of young mothers: Implications for health promotion and cancer prevention Hackshaw-McGeagh, L., Jamie, K., Beynon, R. & O’Neill, R., 1 Apr 2018, In : Health Education Journal. 77, 3, p.277-292

Association between Comorbidity and Survival in Head and Neck Cancer: Results from Head and Neck 5000 Ness, A. R., Schimansky, S., Lang, S., Beynon, R., Penfold, C., Davies, A., Waylen, A., Thomas, S., Pring, M., Pawlita, M. & Waterboer, T., 6 Oct 2018, (Accepted/In press) In : Head and Neck.

Coronary Artery Disease, Genetic Risk and the Metabolome in Young Individuals Battram, T., Hoskins, L., Hughes, D., Kettunen, J., Ring, S., Davey Smith, G., Timpson, N., 12 Sep 2018, In : Wellcome Open Research. 3, , 114

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study Adams, C., Richmond, R. C., Santos Ferreira, D. L. D., Spiller, W., Tan, V. Y., Zheng, J., Wurtz, P., Donovan, J. L., Hamdy, F. C., Neal, D. E., Lane, J. A., Davey Smith, G., Relton, C. L., Eeles, R. A., Henderson, B. E., Haiman, C. A., Kote-Jarai, Z., Schumacher, F. R., Amin Al Olama, A., Benlloch, S., Muir, K., Berndt, S. I., Conti, D. V., Wiklund, F., Chanock, S. J., Gapstur, S. M., Stevens, V. L., Tangen, C. M., Batra, J., Clements, J. A., Grönberg, H., Pashayan, N., Schleutker, J., Albanes, D., Wolk, A., West, C. M. L., Mucci, L. A., Cancel-Tassin, G., Koutros, S., Sørensen, K. D., Maehle, L., Travis, R. C., Hamilton, R., Ingles, S. A., Rosenstein, B. S., Lu, Y-J., Giles, G. G., Kibel, A. S., Vega, A., Kogevinas, M., Penney, K. L., Park, J. Y., Stanford, J. L., Cybulski, C., Nordestgaard, B. G., Brenner, H., Maier, C., Kim, J., John, E. M., Teixeira, M. R., Neuhausen, S. L., DeRuyck, K., Razack, A., Newcomb, L. F., Lessel, D., Kaneva, R. P., Usmani, N., Claessens, F., Townsend, P., Gago Dominguez, M., Roobol, M. J., Menegaux, F., Khaw, K-T., Cannon-Albright, L. A., Pandha, H., Thibodeau, S. N. & Martin, R. M., 23 Oct 2018, In : Cancer Epidemiology, Biomarkers and Prevention.

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference Corbin, L. J., Tan, V. Y., Hughes, D. A., Wade, K. H., Paul, D. S., Tansey, K. E., Butcher, F., Dudbridge, F., Howson, J. M., Jallow, M. W., John, C., Kingston, N., Lindgren, C. M., O'Donavan, M., O'Rahilly, S., Owen, M. J., Palmer, C. N. A., Pearson, E. R., Scott, R. A., Van Heel, D. A., Whittaker, J., Frayling, T., Tobin, M. D., Wain, L. V., Smith, G. D., Evans, D. M., Karpe, F., McCarthy, M. I., Danesh, J., Franks, P. W. & Timpson, N. J., 19 Feb 2018, In : Nature Communications. 9, 1, , 711

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study Adams, C., Richmond, R. C., Santos Ferreira, D. L. D., Spiller, W., Tan, V. Y., Zheng, J., Wurtz, P., Donovan, J. L., Hamdy, F. C., Neal, D. E., Lane, J. A., Davey Smith, G., Relton, C. L., Eeles, R. A., Henderson, B. E., Haiman, C. A., Kote-Jarai, Z., Schumacher, F. R., Amin Al Olama, A., Benlloch, S., Muir, K., Berndt, S. I., Conti, D. V., Wiklund, F., Chanock, S. J., Gapstur, S. M., Stevens, V. L., Tangen, C. M., Batra, J., Clements, J. A., Grönberg, H., Pashayan, N., Schleutker, J., Albanes, D., Wolk, A., West, C. M. L., Mucci, L. A., Cancel-Tassin, G., Koutros, S., Sørensen, K. D., Maehle, L., Travis, R. C., Hamilton, R., Ingles, S. A., Rosenstein, B. S., Lu, Y-J., Giles, G. G., Kibel, A. S., Vega, A., Kogevinas, M., Penney, K. L., Park, J. Y., Stanford, J. L., Cybulski, C., Nordestgaard, B. G., Brenner, H., Maier, C., Kim, J., John, E. M., Teixeira, M. R., Neuhausen, S. L., DeRuyck, K., Razack, A., Newcomb, L. F., Lessel, D., Kaneva, R. P., Usmani, N., Claessens, F., Townsend, P., Gago Dominguez, M., Roobol, M. J., Menegaux, F., Khaw, K-T., Cannon-Albright, L. A., Pandha, H., Thibodeau, S. N. & Martin, R. M., 23 Oct 2018, In : Cancer Epidemiology, Biomarkers and Prevention.

Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions Spiller, W., Slichter, D., Bowden, J. & Davey Smith, G., 23 Aug 2018, (Accepted/In press) In : International Journal of Epidemiology.

Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression  Bowden, Jack; Spiller, Wesley; Del Greco M, Fabiola; Sheehan, Nuala; Thompson, John; Minelli, Cosetta; Davey Smith, George.

Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions Spiller, W., Davies, N. & Palmer, T. M., 15 Aug 2018, (Accepted/In press) In : International Journal of Epidemiology.

Plasma glutathione suggests oxidative stress is equally present in early and late onset bipolar disorder Singh, N., McMahon, H., Bilderbeck, A., Reed, Z., Tunbridge, E., Brett, D., Geddes, J., Churchill, G. & Goodwin, G., 30 Mar 2018, In : Bipolar Disorders.

Correlates of high-impact physical activity measured objectively in older British adults - PubMed (nih.gov) Elhakeem A, Hannam K, Deere KC, Hartley A, Clark EM, Moss C, Edwards MH, Dennison E, Gaysin T, Kuh D, Wong A, Fox KR, Cooper C, Cooper R, Tobias JH.

Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression - PubMed (nih.gov) Bowden J, Spiller W, Del Greco M F, Sheehan N, Thompson J, Minelli C, Davey Smith G.

Software Application Profile: mrrobust - a tool for performing two-sample summary Mendelian randomization analyses Spiller, W., Davies, N. & Palmer, T. M., International Journal of Epidemiology, Sept 2018. 

2018 Publications

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