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16 Meta Analysis

Learning outcomes

On watching this video students should be able to:

  1. State the information that is needed to perform a meta-analysis
  2. Describe the key conceptual differences behind a fixed effects and random effects meta-analysis and explain when one may be preferred over the other.
  3. Describe what is meant by study heterogeneity & interpret an I-squared statistic.
  4. Interpret a forest plot.
  5. State how heterogeneity can be explored within a meta-analysis.
  6. List the limitations of systematic reviews and meta-analysis (eg; “rubbish in, rubbish out” -if all original studies are biased then you’ll just get a more precise biased estimate)
  7. Understand what publication bias is and how to interpret a funnel plot