Activity 5

Randomised Controlled Trial

A randomised controlled trial was conducted to establish the effectiveness and cost-effectiveness of the Healthlines Service.  It involved over 1250 patients in total, 609 with depression and 641 at high risk of cardiovascular disease.  Patients were recruited from 34 participating practices in or around Bristol and Sheffield, and randomised to either the Healthlines Service or usual care.  Outcomes were measured at baseline, and patients were followed up for 12 months using questionnaires and data collected from GP records. 

The research activity was conducted by researchers at the Universities of Bristol and Sheffield. The Healthlines Service was originally delivered by NHS Direct, and towards the end of the study by Solent NHS Trust after NHS Direct closed.