Ada Lovelace day20 November 2015On the 18th November, the Equality & Diversity and Widening Participation offices welcomed over 100 schoolchildren to take part in a Science Showcase as part of the University's celebrations of Ada Lovelace's 200th birthday.
Bristol Biochemistry undergraduate student wins poster prize7 October 2015Congratulations to Rebecca Dixon-Steele, one of our final year undergraduate students, on winning the best poster prize at the Drug Discovery 2015 conference in Telford, organised by ELRIG. Rebecca gave a 10 minute presentation in a poster taster session in the ‘Innovation in Assay Development and Screening’ track, winning her the best poster prize.
DNA shredding by a bacterial enzyme22 September 2015The integrity of the genetic information stored in DNA relies on maintenance of its double-stranded structure. Nonetheless, cells sometimes need to break DNA by cutting each of the polynucleotide strands. These DNA cleavage events are catalysed by enzymes called nucleases; nature’s molecular scissors. Many nucleases are complexes of two proteins, one subunit to cut each DNA strand (i.e., each subunit is a blade of the molecular scissors). A dimer structure ensures that the cuts are close together, leading to a simple DNA break. A collaboration between research teams in Bristol and Pune, India, has now revealed an alternative mechanism, where a pair of nuclease subunits are held distantly apart and the DNA cleavage is more ragged.