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A CRISPR view of MultiBac 4 May 2016 Multigene delivery and subsequent cellular expression is a key technology for a wide range of applications in biology including structural research, cellular reprogramming and functional pharmaceutical screening. The construction of multigene circuits in mammalian cells is a core concept in synthetic biology and requires efficient delivery of complex heterologous DNA. For certain cell types including widely used HEK293 and HeLa cells, this can be achieved by plasmid-based transfection. However, a large number of cell lines and particularly primary cells are recalcitrant to plasmid transfection, thus requiring a different approach. Primary cells are a central focus of current biological research efforts and multigene delivery in primary cells is highly desirable, but suitable tools were markedly lacking to date.
  • A CRISPR view of MultiBac 4 May 2016 Multigene delivery and subsequent cellular expression is a key technology for a wide range of applications in biology including structural research, cellular reprogramming and functional pharmaceutical screening. The construction of multigene circuits in mammalian cells is a core concept in synthetic biology and requires efficient delivery of complex heterologous DNA. For certain cell types including widely used HEK293 and HeLa cells, this can be achieved by plasmid-based transfection. However, a large number of cell lines and particularly primary cells are recalcitrant to plasmid transfection, thus requiring a different approach. Primary cells are a central focus of current biological research efforts and multigene delivery in primary cells is highly desirable, but suitable tools were markedly lacking to date.
  • Pint of Science returns to Bristol 27 April 2016 Pint of Science returns for another year bringing cutting edge research to pubs all over Bristol. Bristol Biochemistry has contributed speakers and organisers over the years and Bristol Biochemistry postgrad Adam Jellett is one of this years' organisers.
  • Two Bristol Biochemistry undergraduates contribute to new paper in Structure 11 April 2016 The Collinson lab celebrate a new paper, 'Unlocking the Bacterial SecY Translocon', published in the journal Structure.
  • Researchers to investigate the origins of bile duct cancer 9 March 2016 Dr Kevin Gaston and Dr Sebastian Oltean at the University of Bristol are working with counterparts at the University of Birmingham and the Chulabhorn Research Institute in Thailand to identify new ways of detecting and treating a form of bile duct cancer that is claiming more and more lives in the UK and across South-East Asia.
  • Biochemistry B-floor Labs Opening 29 February 2016 Christiane Berger-Schaffitzel and Imre Berger, two recent additions to the School of Biochemistry, hosted a gathering celebrating the refurbishment of the new Berger-Schaffitzel laboratories on B-floor
  • Taking Biochemistry to Schools 24 February 2016
  • HEA Fellowship for Bristol Biochemistry Senior Teaching Fellow 2 February 2016 Dr Gus Cameron, from the School of Biochemistry, has been made a Senior Fellow of the Higher Education Academy (HEA) in recognition of his established record in teaching and learning.
  • BTec students solve forensic mystery in Bristol Biochemistry 17 December 2015 On 9th December 2015, BTec students from North Bristol Post-16 Centre visited the School of Biochemistry Teaching labs to try their hand at biochemistry research techniques and solve a forensics scenario.
  • Art of Science 2015 20 November 2015
  • Ada Lovelace day 20 November 2015 On the 18th November, the Equality & Diversity and Widening Participation offices welcomed over 100 schoolchildren to take part in a Science Showcase as part of the University's celebrations of Ada Lovelace's 200th birthday.
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