
Mr Peiyuan Huang
BMed, MSc
Expertise
I study how diet, medication use, and other intrauterine exposures affect maternal and child health, using cohorts and health records from multiple countries to generate causal evidence for clinical and public health practice.
Current positions
Research Associate - Wellcome Trust Transition Fellowship
Bristol Medical School (PHS)
Contact
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Biography
With a medical background and an MSc in Nutrition, I previously worked for the Determinants of Adolescent Social Well-being and Health (DASH) cohort study in the UK and the Born in Guangzhou Cohort Study (BIGCS) in China before my PhD studies. My previous research involves the association of nutrition/dietary behaviours with physical and mental health in adolescence and the perinatal period. My PhD research was to look at the causal effect of maternal vegetarian diet during pregnancy on offspring health by applying a range of causal inference techniques such as Mendelian Randomisation (MR), paternal negative control, within-sibling and cross-cohort comparisons, epigenome-wide association study (EWAS), and metabolome-wide association study (MWAS). I also worked on two mini-projects during my PhD - one investigating the impact of maternal coffee consumption on perinatal health and the other exploring potential drug targets for Alzheimer's disease. Now I am working as a postdoc Wellcome Trust Transition Fellow on pregnancy medication use and perinatal health, using national electronic health record (EHR) data from the UK and Sweden.
Research interests
My current research interests include:
- Using nation-wide electronic health record (EHR) data to investigate the impact of pregnancy medication use on maternal and offspring health;
- The impact of maternal exposures (e.g. nutrition and lifestyles) on maternal and offspring health, as well as the underlying mechanisms via epigenetic and metabolic alterations;
- The use of triangulation for causal inference in epidemiological studies;
- The role of diet/nutrition in mental health and the underlying mechanisms;
- Drug discovery, repurposing, and vigilance for Alzheimer's disease.
Publications
Recent publications
01/04/2024Environmental and genetic predictors of whole blood mercury and selenium concentrations in pregnant women in a UK birth cohort
Environmental Advances
Epilepsy and long-term risk of arrhythmias
European Heart Journal
Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth
International Journal of Epidemiology
Maternal caffeine consumption during pregnancy and offspring cord blood DNA methylation
Epigenomics
Assessment of causal effects of visceral adipose tissue on risk of cancers
International Journal of Epidemiology




