Dr Kate Heesom
B.A.(Oxon.), Ph.D.(Bristol)
Expertise
I run the University’s Proteomics Facility, which focuses on the identification of proteins in complex samples and the analysis of changes in protein expression and post-translational modification between different conditions.
Current positions
Senior Research Fellow (Proteomics Facility Director)
Health and Life Sciences Faculty Office
Contact
Press and media
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Research interests
As Director of the University of Bristol Proteomics Facility, I run a core research facility that provides a full range of bespoke proteomics services allowing the isolation, identification and quantitation of proteins of interest for researchers within the University of Bristol and to external academic and industrial clients.
The key services provided by the Facility are:
- Protein identification: we can identify the proteins present in anything from a single gel band up to a total cell lysate or tissue homogenate.
- Quantitative Proteomics (eg. TMT and SILAC) for the analysis of changes in protein levels between different samples or conditions.
- Phospho-Proteomics for the identification of phosphorylated proteins and the analysis of changes in phosphorylation between different samples or conditions.
- Interactome Analysis (eg. AP-MS) for the analysis of protein binding partners.
- Secretome analysis.
- Serum proteomics.
Projects and supervisions
Research projects
Enabling advanced analytics for all users of the proteomics facility
Principal Investigator
Role
Co-Investigator
Managing organisational unit
Bristol Veterinary SchoolDates
01/01/2018 to 08/06/2021
Thesis supervisions
Publications
Recent publications
29/05/2026Combined transcriptomic and proteomic analyses define conserved host signatures during innate immune perturbations in DF-1 chicken fibroblasts
Frontiers in Cellular and Infection Microbiology
Copper-driven mutualism of Candida albicans and Staphylococcus aureus interkingdom biofilms
Microbiology
Pathogenic podocin variants exhibit distinct defects in trafficking, membrane organization, and degradation pathways
European Journal of Cell Biology
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science
An extended network for regulation of heme homeostasis in cells
Proceedings of the National Academy of Sciences of the United States of America



