
Dr Elise Ajay
PhD, BEng
Expertise
4+ years experience recording from nerves (electrophysiology) and understanding how the response of nerve cells can be impacted by different stimuli and disease.
Current positions
Senior Research Associate
School of Physiology, Pharmacology & Neuroscience
Contact
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Biography
I undertook my PhD at the University of Melbourne and the Bionics Institute where I investigated how augmenting cochlear implants with light (i.e., optogenetic stimulation) might improve the hearing experience of users. I recorded the responses of the hearing nerve cells (spiral ganglion neurons) of mice to different light and electrical stimuli, different disease states, and different mechanisms to tease apart which variables result in the most robust, reliable, and temporally precise responses.
After completing my graduate research in 2024, I moved to the University of Bristol where I now work in the Pickering lab to understand the behaviour of sensory nerve cells of pain (nociceptors) and how their behaviour might change in different disease models in rats.
Research interests
I conduct in vivo electrophysiology on nociceptors in rats to understand how different disease states affect their behaviour, and how that might explain diseases such as chronic pain.
The overall goal of my work is to provide a better understanding of the neural dysfunction that underly pain disorders with a view of improving their treatment.
Publications
Recent publications
09/09/2024Combined-electrical optogenetic stimulation but not channelrhodopsin kinetics improves the fidelity of high rate stimulation in the auditory pathway in mice
Scientific Reports
Auditory nerve responses to combined optogenetic and electrical stimulation in chronically deaf mice
Journal of Neural Engineering
Combined optogenetic and electrical stimulation of the sciatic nerve for selective control of sensory fibers
Frontiers in Neuroscience
Spread of activation and interaction between channels with multi-channel optogenetic stimulation in the mouse cochlea
Hearing Research
Emerging therapies for human hearing loss
Expert Opinion on Biological Therapy