
Professor David Wynick
BSc(Hons), MBBS, MD, PhD
Current positions
Professor of Molecular Medicine
Bristol Medical School (THS)
Contact
Press and media
Many of our academics speak to the media as experts in their field of research. If you are a journalist, please contact the University’s Media and PR Team:
Research interests
I am Professor of Molecular Medicine at Bristol University and Consultant in Pain Medicine at the Bristol Royal Infirmary. My principal academic roles are as Director of Bristol Health Partners AHSC and Director of NIHR Bristol Clinical Research Facility.
My research is focused on the epidemiology of chronic pain (CP) which represents a major global burden and has a UK prevalence of 43%. I led: (a) the consortium which generated the UK Biobank CP phenotyping questionnaire, identifying 98,000 participants with CP, and (b) an analysis of CP using the Bristol, North Somerset and South Gloucestershire system-wide dataset of ~800,000 adults. Results demonstrated CP is the second most impactful condition on health services after anxiety/depression, and the most impactful in the over 50s. It is common in women and more deprived populations, with a significant under-representation of all non-white groups/communities. I am currently focused on delivery at scale of pain management programmes in local neighbourhood hubs close to where patients live (rather than in hospital settings) and much earlier in the patient CP journey, maximising participation and minimising disability and medicalisation.
Projects and supervisions
Research projects
High Impact Chronic Pain and UK Biobank: presentation, transitions and targets for intervention
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/05/2022 to 30/04/2025
8066 EBI MRC CiC David Wynick
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/03/2018 to 31/08/2018
Use of the tetracycline-regulated transactivator system to study the role played by galanin in neuropathic pain and sensory neuron survival
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/01/2011 to 01/01/2014
PILOT INDUSTRY COLLABORATION AWARD SCHEME
Principal Investigator
Dates
01/01/2008 to 01/07/2008
THE ROLE OF GALANIN IN THE ADAPTIVE RESPONSE OF THE PERIPHERAL NERVOUS SYSTEMT O INJURY
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/08/2003 to 01/08/2008
Thesis supervisions
Tales of Neurotrophism
Supervisors
Publications
Recent publications
01/01/2017Targeted disruption of the orphan receptor Gpr151 does not alter pain-related behaviour despite a strong induction in dorsal root ganglion expression in a model of neuropathic pain
Molecular and Cellular Neuroscience
Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor
GLIA
Physiology, signaling, and pharmacology of galanin peptides and receptors
Pharmacological Reviews
The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2
Molecular and Cellular Neuroscience
The role of physical activity and psychological coping strategies in the management of painful diabetic neuropathy - A systematic review of the literature
Physiotherapy