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Dr Laura Howe
Dr Laura Howe
BSc(Sus), MSc(Lond), PhD(Lond)
Senior Research Fellow in Epidemiology
Summary
I am a statistical epidemiologist, with expertise in the modelling of repeated measures data. My main interest is in understanding how factors from across the life course come together to influence health and disease. To do this, we need better methods for making the most of the detailed longitudinal data that is collected within cohort studies. I conduct methodological research into statistical methods for life course data, and apply these methods to studies of obesity, cardiometabolic health and healthy ageing. I also have an interest in inequalities in health from a life course perspective, particularly focusing on how socioeconomic differences emerge and change across life and in using longitudinal data to explore what factors might explain them.
Biography
- 2015-2020: MRC Career Development Award
"Mediation analysis in life course epidemiology: methodological innovation and application to studies of obesity and cardiometabolic health"
- 2011-2015: MRC Population Health Scientist fellowship
"Longitudinal modelling of adiposity, its determinants and its consequences"
- 2008-2011: Research Associate
- 2005-2008: PhD student, London School of Hygiene & Tropical Medicine
"The wealth index as a measure of socio-economic position"
- 2004-2005: MSc Epidemiology, London School of Hygiene & Tropical Medicine
Teaching
I am a tutor for the Clinical Epidemiology course for first year medical students and I contribute to several short courses within the Social and Community Medicine (including Introduction to Statistical Methods for Life Course Epidemiology, Analysis of Repeated Measures, Introduction to Statistics). I became a fellow of the Higher Education Academy in August 2014.
Keywords
- longitudinal
- trajectories
- mediation
- growth
- obesity
- cardiovascular
- socio-economic inequalities
Skills
- obesity
- cardiovascular disease
- healthy ageing
Methodologies
Selected publications
- Howe, LD, Parmar, PG, Paternoster, L, Warrington, NM, Kemp, JP, Briollais, L, Newnham, JP, Timpson, NJ, Smith, GD, Ring, SM, Evans, DM, Tilling, K, Pennell, CE, Beilin, LJ, Palmer, LJ & Lawlor, DA, 2013, ‘Genetic Influences on Trajectories of Systolic Blood Pressure Across Childhood and Adolescence’. Circulation: Cardiovascular Genetics, vol 6., pp. 608-614
- Anderson, EL, Tilling, K, Fraser, A, Macdonald-Wallis, C, Emmett, P, Cribb, V, Northstone, K, Lawlor, DA & Howe, LD, 2013, ‘Estimating trajectories of energy intake through childhood and adolescence using linear-spline multilevel models’. Epidemiology, vol 24., pp. 507-515
- Howe, LD, Lawlor, DA & Propper, C, 2013, ‘Trajectories of socioeconomic inequalities in health, behaviours and academic achievement across childhood and adolescence’. Journal of Epidemiology and Community Health, vol 67., pp. 358-364
- Howe, L, Tilling, K, Galobardes, B & Lawlor, D, 2013, ‘Loss to Follow-up in cohort studies: bias in estimates of socioeconomic inequalities’. Epidemiology, vol 24., pp. 1-9
- Howe, L, Matijasevich, A, Tilling, K, Brion, M-J, Leary, S, Smith, GD & Lawlor, D, 2012, ‘Maternal smoking during pregnancy and offspring trajectories of height and adiposity: comparing maternal and paternal associations’. International Journal of Epidemiology, vol 41., pp. 722-732
- Matijasevich, A, Howe, L, Tilling, K, Santos, I, Barros, A & Lawlor, D, 2012, ‘Maternal education inequalities in height growth rates in early childhood: 2004 Pelotas birth cohort study’. Paediatric and Perinatal Epidemiology, vol 26 (3)., pp. 236 - 249
- Howe, LD, Tilling, K, Matijasevich, A, Petherick, ES, Santos, AC, Fairley, L, Wright, J, Santos, IS, Barros, AJD, Martin, RM, Kramer, MS, Bogdanovich, N, Matush, L, Barros, H & Lawlor, DA, 2013, ‘Linear spline multilevel models for summarising childhood growth trajectories: A guide to their application using examples from five birth cohorts’. Statistical Methods in Medical Research.
- Warrington, NM, Howe, LD, Paternoster, L, Kaakinen, M, Herrala, S, Huikari, V, Wu, YY, Kemp, JP, Timpson, NJ, St Pourcain, B, Smith, GD, Tilling, K, Jarvelin, M-R, Pennell, CE, Evans, DM, Lawlor, DA, Briollais, L & Palmer, LJ, 2015, ‘A genome-wide association study of body mass index across early life and childhood’. International journal of epidemiology, vol 44., pp. 700-712
- Kipping, RR, Howe, LD, Jago, R, Campbell, R, Wells, S, Chittleborough, CR, Mytton, J, Noble, SM, Peters, TJ & Lawlor, DA, 2014, ‘Effect of intervention aimed at increasing physical activity, reducing sedentary behaviour, and increasing fruit and vegetable consumption in children: Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial’. BMJ, vol 348.
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Recent publications
- Araújo, FA, Martins, A, Alegrete, N, Howe, LD & Lucas, R, 2017, ‘A shared biomechanical environment for bone and posture development in children’. European Spine Journal.
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