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Professor Stuart Mundell

Professor Stuart Mundell

Professor Stuart Mundell
B.Sc.(Glas.), Ph.D.(Bristol)

Professor in Cellular Pharmacology

Area of research

G protein-coupled receptor function and signalling in atherothrombosis

Office C7a
Biomedical Sciences Building,
University Walk, Bristol BS8 1TD
(See a map)

Tel. +44 (0) 117 331 1440

Research summary

G protein-coupled receptor function and signalling in atherothrombosis

G protein-coupled receptors (GPCRs), one of the largest protein families in the human genome, are the most tractable set of therapeutic targets for novel drug design. These cell surface expressed proteins translate extracellular cues which bombard the cell surface into signals which determine cellular function. GPCRs are regulated in a dynamic and complex manner, and are not static entities inserted into the plasma membrane of cells. My research examines the cell specific signals produced by individual GPCRs and the complex regulatory mechanisms controlling GPCR signalling, surface expression and intracellular sorting.  Further ...

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Recent publications

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