Dr Andy Salmon

Research summary

Albuminuria, the leak of albumin into urine, is a major health problem, since it is related to both cardio-vascular disease and progression of kidney disease. Kidneys filter blood to produce essentially albumin-free urine - less than 1 in 2,500 albumin molecules cross the wall of kidney filters (specialised blood capillaries called glomeruli). People with even a subtle increase in albuminuria are at increased risk of dying from cardiovascular disease: the risk independently conferred by albuminuria approaches the risk conferred by smoking. In addition, many primary kidney diseases are characterised by excessive albu-minuria. The presence of albumin in the urine is ...

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Biography

Andy Salmon trained in clinical medicine at the University of Bristol, graduating in 1998. Junior doctor posts in general medicine in the South West of England, Nottingham and New Zealand were followed by a Wellcome Trust Research Training Fellowship in the Microvascular Research Laboratories in the Department of Physiology in Bristol, leading to a PhD examining intrinsic regulation of glomerular permeability. He undertook a Clinical Lectureship in Nephrology at the Academic Renal Unit in Bristol, alongside Specialist Registrar training in Nephrology. He took up a Medical Research Council and Academy of Medical Sciences-funded Clinician Scientist Fellowship in December 2009, based ...

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Selected publications

• Qiu, Y, Ferguson, J, Oltean, S, Neal, CR, Kaura, A, Bevan, HS, Wood, E, Sage, LM, Lanati, S, Nowak, DG, Salmon, AHJ, Bates, DO & Harper, SJ. ‘Overexpression of VEGF165b in podocytes reduces glomerular permeability’, J Am Soc Nephrol, 21(9), (pp. 1498-1509), 2010
• Salmon, AHJ, Neal, CR & Harper, SJ. ‘New aspects of glomerular filtration barrier structure and function: five layers (at least) not three’, Curr Opin Nephrol Hypertens, 18(3), (pp. 197-205), 2009

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Recent publications

• Salmon, AHJ & Satchell, SC. ‘Endothelial glycocalyx dysfunction in disease: albuminuria and altered microvascular permeability’, Journal of Pathology, 2011
• Salmon, AHJ. ‘GPs should be vigilant for glomerulonephritis’, Practitioner, 254(1728), (pp. 27-32), 2010

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View complete publications list in the University of Bristol publications system